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OCTENISEPT SPRAY

OCTENISEPT SPRAY
OCTENISEPT SPRAY
OCTENISEPT SPRAY
OCTENISEPT SPRAY
OCTENISEPT SPRAY
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Octenisept 1 mg/g + 20 mg/g cutaneous solution is a topical antiseptic containing octenidine dihydrochloride and phenoxyethanol. The active substa..
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  • Stock: Zabrana online prodaje
  • Brand: SCHULKE
  • Model: BR-654165414

Octenisept 1 mg/g + 20 mg/g cutaneous solution is a topical antiseptic containing octenidine dihydrochloride and phenoxyethanol. The active substances inhibit the growth of and destroy selected microorganisms on the skin and mucous membranes.

It is used for repeated, short-term antiseptic treatment of mucous membranes and surrounding skin before selected diagnostic or surgical procedures, as supportive antiseptic treatment of wounds and as temporary supportive treatment of fungal infection between the toes.

Important warning
Octenisept is for local external use only. It must not be injected or introduced into tissue under pressure and must not be used to irrigate deep wound pockets with a syringe. Incorrect pressurised application may cause persistent swelling, redness and tissue necrosis.

Octenisept spray – indications, correct use and precautions

Information Details
Active substances Octenidine dihydrochloride 1 mg/g and phenoxyethanol 20 mg/g
Dosage form Clear to almost clear, colourless cutaneous solution
Spray packs 50 ml and 250 ml
Main uses Short-term antiseptic treatment of mucous membranes and adjacent skin, supportive wound treatment and supportive treatment of interdigital fungal infection
Contact time At least 1–2 minutes before a dressing or another procedure
Maximum use without supervision Up to 14 days
Legal status Available without a prescription

What is Octenisept used for?

  • short-term antiseptic treatment of mucous membranes and surrounding skin in the anogenital region, including the vagina, vulva and glans penis;
  • antiseptic preparation before urinary-bladder catheterisation;
  • short-term antiseptic treatment of the oral cavity;
  • supportive antiseptic treatment of wounds;
  • temporary supportive treatment of fungal infection between the toes.

Octenisept is not intended for routine daily intimate hygiene, prolonged irrigation of mucous membranes or independent treatment of a deep or seriously infected wound.

How is it applied?

The solution is normally applied once daily to mucous membranes and surrounding skin. Application with a fully soaked sterile swab is preferred, while the spray pump may be used on areas that are difficult to reach.

  1. Wash and dry your hands.
  2. Remove visible contamination carefully as instructed by a healthcare professional.
  3. Moisten the entire treatment surface without vigorous rubbing.
  4. Spray evenly onto areas that cannot easily be reached with a swab.
  5. Allow a contact time of at least one to two minutes.
  6. Only then apply a dressing or continue with another procedure.

Do not use more solution than is required to wet the surface. Remove excess solution before applying an occlusive dressing.

Use on wounds

Octenisept is used as supportive antiseptic treatment of wounds. It may be part of the care of minor superficial injuries, but cleaning, dressing selection and dressing-change frequency depend on the type of wound.

Do not inject the solution, introduce it through a cannula or force it into a deep wound cavity. Free drainage of the solution must always be possible.

Medical assessment is required for:
  • a deep, puncture, bite or heavily contaminated wound;
  • heavy or prolonged bleeding;
  • spreading redness, swelling or pain;
  • pus, offensive odour or fever;
  • an extensive burn;
  • a wound in a patient with diabetes, poor circulation or impaired immunity;
  • a wound that does not show expected signs of healing.

Fungal infection between the toes

For supportive treatment of interdigital fungal infection, spray the affected areas in the morning and evening.

Dry carefully between the toes, change socks every day and allow footwear to dry fully. Octenisept is supportive treatment in this indication and does not necessarily replace an appropriate antifungal medicine.

Use in the oral cavity

Oral rinsing is limited to cases where the entire oral cavity must be treated. The approved instructions specify 20 ml of solution for 20 seconds.

Do not swallow the solution. It may cause a temporary bitter taste. Prolonged daily mouth rinsing without professional advice is not recommended.

Where must Octenisept not be used?

  • it must not be injected or introduced into the bloodstream;
  • it must not be forced into tissue under pressure;
  • it must not be used to rinse the abdominal cavity;
  • it must not be used to rinse the urinary bladder;
  • it must not be used to rinse the ears or on the eardrum;
  • contact with the eyes must be avoided;
  • swallowing is not recommended.

Rinse the eyes immediately with plenty of water after accidental contact and seek medical advice if irritation continues.

Use in children

The leaflet does not state a specific minimum age, but particular caution is required in premature infants with low birth weight.

Excessive amounts or prolonged contact with soaked materials may cause serious skin damage. Remove excess solution and do not leave soaked clothing, cloths or pads in prolonged direct contact with the skin.

Pregnancy and breastfeeding

Pregnancy data are limited, although currently available information does not indicate an increased risk to the unborn child. Use may be considered when necessary after advice from a doctor or pharmacist.

Breastfeeding data are also limited. Octenidine is absorbed only minimally or not at all, and accumulation of phenoxyethanol in breast milk is considered unlikely. Seek professional advice before extensive use or application close to the breast.

Interaction with PVP-iodine

Do not apply Octenisept next to antiseptics containing povidone-iodine or PVP-iodine. Dark-brown to purple discolouration may occur where the two solutions meet.

Do not independently apply several antiseptics to the same area. The combination may increase irritation without improving wound care.

Possible side effects

Rare effects include burning, redness, itching and warmth at the application site.

A local allergic reaction, such as temporary redness, is very rare. Oral rinsing may cause a temporary bitter taste.

Persistent swelling, redness and tissue necrosis have been reported after incorrect irrigation of deep wounds with a syringe.

Stop use and seek medical help for:
  • marked or rapidly increasing swelling;
  • severe pain or sudden worsening of a wound;
  • difficulty breathing;
  • swelling of the face, lips, tongue or throat;
  • widespread hives or another severe allergic reaction.

How long may it be used?

Octenisept should not be used continuously for longer than 14 days without medical supervision.

Consult a doctor if the condition does not improve, becomes worse or repeatedly returns.

Pharmacist’s advice
For a superficial wound, first control bleeding with gentle pressure using clean gauze and carefully remove visible dirt. Apply Octenisept until the surface is evenly moist and allow at least one to two minutes before covering it. Do not touch the wound with the spray nozzle. Deep, bite, puncture or heavily contaminated wounds require medical assessment and a review of tetanus protection. Skin-repair products are selected according to the healing stage and do not replace examination when signs of infection are present.

Ljubica Barbulović, Master of Pharmacy

Availability and price

Octenisept is available without a prescription. The ApotekaOnline product page is currently marked as unavailable for online sale. Check current availability and price directly with the pharmacy or on the Octenisept spray information page.

Related wound care

Related products are available in the following categories:

Related products:

These products serve different purposes and should not automatically be layered over one another. Product selection depends on whether the wound needs cleansing, protection, absorption of exudate or support during skin repair.

Related blog topic: What is the best treatment for pressure sores and open wounds?

Composition, appearance and pack sizes

Each 100 g of solution contains:

  • 0.1 g of octenidine dihydrochloride;
  • 2.0 g of phenoxyethanol.

Other ingredients are cocamidopropyl betaine, sodium gluconate, glycerol 85%, sodium chloride, sodium hydroxide 10% solution and purified water.

  • 50 ml spray bottle: EAN 4032651214358;
  • 250 ml spray bottle: EAN 4032651214570;
  • 1000 ml bottle with safety closure: EAN 4032651214587.

Marketing authorisation holder: Polifarm d.o.o. Belgrade, Serbia.
Manufacturer: Schülke & Mayr GmbH, Norderstedt, Germany.

Storage

Store below 25°C and keep out of the sight and reach of children. Do not freeze.

After first opening, the bottle may be used for up to three years, but not beyond the expiry date printed on the packaging.

Frequently asked questions

Is Octenisept an antibiotic?
No. It is a topical antiseptic and disinfectant, not a systemic antibiotic.

Can it be used on superficial wounds?
It may be used as supportive antiseptic wound treatment. Deep, heavily contaminated, bite or infected wounds require assessment.

How long should it remain on the surface?
The area must remain fully moistened for at least one to two minutes before dressing or another procedure.

May it be sprayed into a deep wound?
No. It must not be injected or forced under pressure into deep tissue or a closed wound cavity.

Can it be used for fungal infection between the toes?
It may be used as temporary supportive treatment in the morning and evening, but it does not always replace an antifungal medicine.

Can it be used in the ear?
No. It must not be used to rinse the ear or on the eardrum.

Can it be combined with povidone-iodine?
They should not be used on adjacent areas because brown-to-purple discolouration may occur where the solutions meet.

How long can it be used without medical supervision?
For no longer than 14 days.

How long is it usable after opening?
For up to three years when stored correctly and provided the printed expiry date has not passed.

Official sources: ALIMS – Patient Information Leaflet | ALIMS – Summary of Product Characteristics.
The authorisations for the 50 ml, 250 ml and 1000 ml packs were renewed on 27 May 2025 and are valid until 27 May 2030. Official leaflet approved in May 2025. Content checked: August 2026.

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For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.

Deliveries are not made on Saturdays and Sundays.

Additional information

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Shipping cost

For the territory of the Republic of Serbia:

For goods ordered up to 5.000,00 RSD, delivery charge is 260.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.

For international delivery:

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  • Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
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Delivery time is 15 days or more (depending on the country of delivery)

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