GOLDEN TEA-SAGE

Sage (Salvia officinalis) is known as the karminativ, an anti-spasmodic and astringent. It is normally used for cases of dyspepsia, pharyngitis, stomatitis, gingivitis, glositis, hiperhidrotik, galaktoroik (Barnes et al., 2007).

Are registered and used for backup memory. The German Commission (The German Commission E) has approved the use of Sage for internal use for dispeptične symptoms and for excessive sweating, and for mouth and throat mucous membrabe for external use, IE. for rinsing.

 Preparation

Taking a čajšiku ® Sage list, close the cover and wet underneath of cold water (this is important to cell membranes burst and multiple active components are acquitted, are also in this way prevents the flotation device najsitnih particles and their plutanjenje by area.) Čajšiku down to the prokuvane and prohlađene 200 ml water. After 5-10 minutes to drink one Cup three times a day or used for irrigation. It is important to always use fresh infuz.

Dosing

infuz 1-1.5 g 3-4 times a day

inhalation 2-3 g 5-10 min

for rinsing mucous membranes 2-3 g grgoljiti more than once per 30 sec

An active substance and mechanism of medicinal effects

Essential oils, monoterpenoidi, sesquiterpenes (thujone, camphor, caryophyllene, cineole, humulen, limonene, menthol, etc.), derivatives of hidroksicinamične acid, kafeična, trihidroksicinamična,, karnozati sageon, terpenes, flavonoids, luteolin, apigenin, polysaccharides, phytosterols, etc.

Antibacterial, fungistatilni, antiseptic and virustatski effects

Up to now it has been proven that the effect of Sage essential oil has antimicrobial properties, thanks to the tujonu (Bradley, 2006; Newall et al., 1996). Inhibitory effect was observed in gram positive and gram negative bacteria: Escherichia coli, Shigella sonnei, Salmonella species, Klebsiella ozanae (Gram-negative), Bacillus subtilis (Gram-positive), and to the strains of the fungus Candida albicans, C. order, c. pseudotropicalis, Torulopsis glabrata, Cryptococcus neoformans.

In studies (Horiuchi | et al., 2007) has been reported to the raw extract Salvia officinalis l. showing antimicrobial activity against Vancomycin-resistantnog enterococci (VRE). In this case, is the frontrunner for the antimicrobial activity is considered to oleanolična acid. Ursolična acid also shows activity according to TI, as well as Streptococcus pneumonia and Methicillin-resistant Staphylococcus aureus (MRSA). In vitro antibacterial activity is recorded and the Lactobacillus curvatus, Lactobacillus sakei, Staphylococcus carnosus, Staphylococcus xylosus, Enterobacter gergoviae and Enterobacter amnigenus.

A Sage extract showed strong inhibitory effect of Porphyromonas gingivalis (ESCOP, 2003).

Diterpeni saficinolid and sagon showed activity in the vesicular stomatitis virus (Bradley, 2006; Wichtl, 2004).

Antioxidant effect

Studies (Chang et al. 1977) is a proven reduction of peroxide as a antioksiativne activity of water extracts of Sage leaf.

Controlled stability of soybean oil with and without extract of Sage leaf and it has been long maintaining taste on the treated sample. It is assumed that the antioxidant activity originates from the 1-O-(2, 3, 4-trihidroksi-3-methil) butyl-6-O-feruloil-β-D-glukopiranozida, ethyl β-D-glucopiranozil tuberonata, p-hidrksibenzoične acid, (-)-hidroksijasmonične acid, kafeične acid and 4-hidroksiacetofenon 4-O-[5-O-(3,5-dimetoksi-4-hidroksibenzoil)-β-dapiofrunozil]-(1f2)-β-D-glukopiranozida; (Wang et al., 2000). At a concentration of 30 µ M all substances have shown activity in bondage free radicals (with kafeičnom acid as najaktivnijom).

Sage extract showed a greater antioxidant activity than Ascorbic acid (vitamin C) (Muchuweti et al., 2007).

The study, which has antioxidant properties and hipoholesterolemijsku function of rats used a tea of Sage. Rats were divided into 4 groups,

control group;
Group fed a regular diet and tea extracts;
a group that was fed a high cholesterol diet rich kaloričnom;
Group fed with visokoholesterolskom diet and tea extracts.
Transaminases, cholesterol, triglycerides, LDL, and lipid peroxides, GSH, and enzymes, glutathione-S-transferase (GST) and Glutathione reductase (GR) were measured in order to safeguard safety and effectiveness measured activities Sage at hiperholesterolemiju. Groups who wrote infuz Sage had a significant reduction in total cholesterol, triglycerides, LDL and lipid peroxide. The same study showed that there was no inherent toxicity in the liver of rats or unwanted effects. It's an interesting phenomenon to increase the activity of antioksidantnih enzymes of the liver GSH, GST, and Gr. concluded that phytosterols have antioxidant and protektivnu feature in the treatment of hiperholesterolemija (El-Desouki et al., 2007)

Anti-inflammatory/Antiflogistički effect

Sage extract reduced edema caused by ear mouse in vivo, is also provided and find out an addiction. This effect is achieved thanks to ursoličnoj acid (ID50 µ: 0.14 M/cm2), which is shown twice as strong effect of indomethacin (ID50 µ: 0.26 M/cm2) (ESCOP, 2003; Wichtl, 2004).

The same effect but with less activity is shown and oleanolična acid (ID50 µ: 0.36 M/cm2) (ESCOP, 2003). Ruzmarinska acids has shown anti-inflammatory effects after topical application to the damaged gingiva monkeys. There is a significant reduction of the gingival lesions compared with placebo. (Van Dyke et al., 1986).

Antitusična and imunomodulatorna activity of pectin and hemiceluloznih polisharida originally from Sage list are tracked in the study (Sutovska et al., 2007). Polisaharidni complex and significantly reduced the number of attempts to cough (RP) as well as the intensity of inspiratornog and expiratory attack (IN-and EN +) with mechanically-induced cough in cats without unwanted effects EMMA/HMPC/330383/2008 © EMEA 2010 Page 17/39. In the same conditions of the compared the activity opiodnih, neopiodnih medication and drug infusion Sage. Sage had effect only 13% less of codeine with the difference that the mucosa treated water extract of Sage timocita noticed proliferative activity, which underlines the added feature polisharida imunomodulatornu isolated leaf Sage. (Bradley 2006).

Carminative, spazmolitični, exhilarating and tonic effect on the digestion and nervous system

Sage is showing some stimulating effects on trahealne and ilealne smooth muscles, although visibly fewer than extracts of leaf Melissae off. (Bradley, 2006). The effect is attributed to the pinenima who prevent download free Ca2 +. The study on Guinea Pigs spotted the activity at antispazmotička Oddi sphincter spasm induced by morphine. (Todorov et al., 1984).

The study (Kennedy et al. 2006) followed by the effect of the inhibition of cholinesterase (ChE) list of S. officinalis and influence on mood, anxiety and concentration. Ekstarkt showed a dose-dependent inhibitory ChE trait, with greater selectivity for BuChE (butirilholinesterazu) (IC50:0054 mg/ml). In this connection he and mild hypotensive activity extract showed the cats. Hypotension was moderate, but with extended influence (Todorov et al., 1984).

With every purchased tea as a gift you receive ČAJŠIKU

http://zlatnicajevi.rs/cajsika