-150x150w.webp)
-150x150w.webp)
Nasonex 50 micrograms per spray, 140 doses – mometasone for allergic rhinitis and nasal polyps
Pogledajte blok ispod gde možete pronaći proizvode koji su slični ili imaju slična dejstva kao proizvod na čijoj se stranici nalazite.
- Stock: Zabrana online prodaje
- Brand: ORGANON
- Model: BR-605667688
Prilinda Plus is a prescription medicine containing two active ingredients – ramipril and hydrochlorothiazide. It is available as 2.5 mg/12.5 mg and 5 mg/25 mg tablets, with 28 tablets in each pack.
Ramipril is an ACE inhibitor that relaxes and widens blood vessels. Hydrochlorothiazide is a thiazide diuretic that increases the removal of water and salts in the urine. Together, these actions help lower blood pressure.
The fixed combination is used in adults whose blood pressure has not been adequately controlled by ramipril or hydrochlorothiazide used separately.
Do not start, change or stop Prilinda Plus without medical instruction. The selected strength depends on previous treatment, blood-pressure readings, kidney and liver function and blood-electrolyte levels.
Swelling of the lips, tongue, face or throat and difficulty breathing or swallowing may indicate angioedema. Stop treatment and seek urgent medical help.
Prilinda Plus – administration, dosage and major precautions
What is Prilinda Plus used for?
Prilinda Plus is used for arterial hypertension when treatment with either ramipril or hydrochlorothiazide alone has not provided adequate blood-pressure control.
It is normally introduced after the prescriber has assessed the dose requirements of the individual components. It is not a medicine to take occasionally only when a reading is high.
How is it taken?
- Take the prescribed tablet once daily, usually in the morning.
- Take it at approximately the same time each day.
- It may be taken with or without food.
- Swallow with sufficient liquid.
- Do not chew or divide the tablet to produce a smaller dose.
- Do not take a double dose after a missed dose.
The score line is intended only to make the tablet easier to break for swallowing. It does not provide two equal doses.
Older patients and patients with impaired kidney or liver function may require a lower dose and closer monitoring. Use is not recommended in patients under 18 years.
When must the medicine not be used?
- allergy to ramipril, hydrochlorothiazide, another ACE inhibitor, thiazide, sulfonamide or excipient;
- a previous episode of angioedema;
- combined use with sacubitril/valsartan;
- severe kidney impairment with creatinine clearance below 30 mL/min;
- significant renal-artery narrowing;
- severe liver impairment or hepatic encephalopathy;
- a clinically significant sodium, potassium or calcium disturbance;
- the second or third trimester of pregnancy;
- breastfeeding;
- aliskiren use in patients with diabetes or impaired kidney function.
A gap of at least 36 hours is required when switching between Prilinda Plus and sacubitril/valsartan.
Monitoring
The doctor may monitor blood pressure, kidney function, creatinine, potassium, sodium, magnesium, calcium, glucose, uric acid, lipids and blood-cell counts.
Ramipril may increase potassium, while hydrochlorothiazide may decrease it. Do not take potassium supplements, potassium-containing salt substitutes, magnesium, herbal diuretics or “water-loss” products without professional approval.
Dehydration and low blood pressure
Vomiting, diarrhoea, excessive sweating, a very low-salt diet, reduced fluid intake or another diuretic may increase the risk of hypotension and kidney impairment.
Contact a doctor if prolonged vomiting or diarrhoea occurs. Do not change the treatment plan without individual instructions.
Important interactions
- NSAIDs such as ibuprofen and diclofenac may reduce the blood-pressure effect and increase kidney risk.
- Potassium supplements, potassium-sparing diuretics, trimethoprim, ciclosporin and tacrolimus may increase potassium.
- Other diuretics, corticosteroids, stimulant laxatives and amphotericin B may reduce potassium.
- Lithium toxicity may increase.
- Diabetes medicines may require dose adjustment.
- Other antihypertensives, nitrates, anaesthetics, certain antidepressants and alcohol may cause excessive hypotension.
- Heart-rhythm medicines and digoxin require caution when electrolytes change.
Pregnancy and breastfeeding
Women planning pregnancy should be transferred to an appropriate alternative treatment. Use is not recommended during the first trimester and is contraindicated after the third month of pregnancy.
Contact the prescriber immediately if pregnancy occurs. Prilinda Plus must not be used during breastfeeding.
Possible side effects
Common effects include headache, weakness, tiredness, dizziness, dry irritating cough, bronchitis and increases in glucose, uric acid or blood lipids.
Low blood pressure, fainting, nausea, abdominal discomfort, increased urination, thirst, electrolyte changes, kidney impairment, rash, palpitations and changes in blood-cell counts may also occur.
- swelling of the face, lips, tongue or throat;
- difficulty breathing or swallowing;
- blistering, peeling skin or mouth ulcers;
- severe abdominal pain spreading to the back;
- yellow skin or eyes;
- sudden visual reduction or severe eye pain;
- shallow breathing, fever, weakness and confusion;
- fainting, severe hypotension or an abnormal heartbeat;
- markedly reduced urine production;
- fever, sore throat, repeated infections, bruising or unusual bleeding.
Composition and packs
- 2.5 mg/12.5 mg: 2.5 mg ramipril and 12.5 mg hydrochlorothiazide per tablet.
- 5 mg/25 mg: 5 mg ramipril and 25 mg hydrochlorothiazide per tablet.
- Pack: 28 tablets in four blisters of seven.
- Relevant excipient: lactose monohydrate.
- Marketing authorisation holder and manufacturer: Hemofarm AD Vršac, Serbia.
- ATC code: C09BA05.
- Supply status: prescription only.
Storage
Keep out of the sight and reach of children and store below 25°C. Do not use after the expiry date stated on the pack.
Prilinda Plus is a prescription-only medicine and cannot be ordered through the online shop. Both strengths are included in the Serbian RFZO List A applicable from 14 April 2026. Check current availability, price and reimbursement conditions directly with a pharmacy.
Take Prilinda Plus every day at the same time, normally in the morning. Do not skip it simply because the current blood-pressure reading is normal.
Do not introduce potassium supplements, salt substitutes containing potassium, herbal diuretics or electrolyte products without checking the complete treatment and laboratory results.
Ljubica Barbulović, Master of Pharmacy
Related category and guide
Explore: High blood pressure – heart and blood-vessel support.
Serbian-language guide: How to lower high blood pressure through lifestyle measures.
Important: dietary supplements do not replace Prilinda Plus or prescribed treatment for diagnosed hypertension.
Is Prilinda Plus taken only when blood pressure is high?
No. It is taken regularly once daily according to the treatment plan.
When should it be taken?
Usually in the morning at the same time each day, with or without food.
Can the tablet be divided into equal doses?
No. The score line does not provide two equal doses.
Can it cause a dry cough?
Yes. A persistent dry cough may be caused by ramipril. Consult the prescriber rather than stopping treatment independently.
Can potassium be taken with it?
Only when specifically prescribed after laboratory assessment.
Source: Official patient leaflet, Summary of Product Characteristics and packaging text approved by the Serbian Medicines and Medical Devices Agency – ALIMS. View the official Prilinda Plus leaflet.
Leaflet last approved: September 2024. RFZO listing checked: August 2026.
This information does not replace medical assessment, blood-pressure measurement, laboratory monitoring, professional advice or the original leaflet.
Pharmacy Online has a contract with the Daily Express courier service and it is delivered on the territory of the Republic of Serbia through this service. Exports of goods to foreign countries are done through DHL and PostExport.
For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.
Deliveries are not made on Saturdays and Sundays.
Additional information
The items will be packed so that they cannot be damaged by normal handling of the goods in transit. When picking up the product, the buyer is obliged to check for any damage and immediately advertise it to the courier who delivered the goods, or refuse to take over the shipment, which shows the external damage. Any subsequent product claims for shipping damage will not be considered.
When picking up the product, the customer is required to sign the delivery note taken by the Daily Express delivery worker. The delivery note is considered to be a receipt and delivery note.
The courier service delivers the goods to the address, ie. does not bring into the living space.
Delivery restrictions on goods
Delivery of items purchased on the site www.apotekaonline.rs is made exclusively through the Daily Express courier service in the territory of the Republic of Serbia. Delivery outside the territory of the Republic of Serbia, ie export of goods, is done exclusively through the service of DHL and PostExport Post of Serbia.
Shipping cost
For the territory of the Republic of Serbia:
For goods ordered up to 5.000,00 RSD, delivery charge is 260.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.
For international delivery:
For the export of goods abroad through the PostExport service of Post of Serbia, the shipping price is for:
- Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
- Zone II (Other European countries) - 1,790.00 RSD
- Zone III (Asia, Africa, America, Australia and other countries) - 2,650.00 RSD
Delivery time is 15 days or more (depending on the country of delivery)
For export of goods abroad through DHL service, the shipping price is 2,700.00 RSD. Delivery time is 1-5 business days (depending on the country of delivery)
Shipping cost is with tax. The price includes the delivery of the parcel to the buyer's address with the associated tax and customs at the seller's expense. A possible additional cost may be a customs charge against the buyer, depending on the country to which the package is being shipped.
For any additional questions, complaints or checking the current location of your shipment, please contact us at the following e-mail address: info@apotekaonline.rs
