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Mendiaxon 200 mg tablets (hymecromone) – pain associated with indigestion
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- Stock: Zabrana online prodaje
- Brand: PHARMANOVA
- Model: BR-6912065260
Mendiaxon is a tablet medicine containing 200 mg hymecromone, a coumarin derivative from the group of bile therapy medicines (ATC A05AX02). According to the current package leaflet (January 2025), Mendiaxon is used for the symptomatic treatment of pain associated with indigestion (dyspeptic disorders).
In Serbia the medicine is available without a prescription and is intended for short-term use – up to 7 days. If symptoms do not improve or get worse after 7 days, see a doctor. Mendiaxon does not dissolve gallstones and does not replace a medical examination for severe or recurrent pain.
Important warning
- Supply status in Serbia: non-prescription medicine.
- Must not be used in bile duct obstruction, acute liver and/or kidney failure, ulcerative colitis or Crohn’s disease.
- Treatment lasts no longer than 7 days; if there is no improvement, consult a doctor.
- Stop treatment if signs of liver or kidney failure appear.
- This page is for information only and is not an offer to buy the medicine online.
When is Mendiaxon 200 mg used and how should it be taken correctly?
Key facts about the medicine
| Name of the medicine | Mendiaxon®, 200 mg, tablets |
|---|---|
| Active substance | hymecromone |
| Strength | 200 mg hymecromone per tablet |
| Pharmaceutical form | tablet (white to yellowish, round, flat, engraved “Ch”) |
| Therapeutic group | bile therapy (ATC A05AX02) |
| Pack | 30 tablets (3 blisters of 10 tablets) |
| Marketing authorisation holder | Pharmanova d.o.o. Obrenovac; manufacturer Adamed Pharma S.A., Pabianice, Poland |
| Supply status (Serbia) | non-prescription medicine |
What is Mendiaxon used for?
According to the official package leaflet and SmPC, Mendiaxon is used for the symptomatic treatment of pain associated with dyspeptic disorders, i.e. with indigestion.
Earlier versions of the text listed broader uses (spasm of the sphincter of Oddi, conditions after gallbladder surgery, uncomplicated gallstones, anorexia, nausea, constipation). The current leaflet approved in January 2025 lists only the indication above. If pain lasts longer, recurs or is severe, a medical examination is needed.
How is it used and dosed?
| Group | Dosing according to the package leaflet |
|---|---|
| Adults | 1 to 2 tablets (200–400 mg) half an hour before meals, three times daily |
| Duration | for a period of one week (7 days) |
| Elderly | no dose adjustment needed |
- The tablets should not be divided.
- Take half an hour before meals.
- The leaflet gives doses for adults only – do not use in children and adolescents without medical advice.
Special patient groups
- Elderly patients: the dose is not changed.
- Liver and/or kidney disease: not used in liver and/or kidney failure.
- Children: the official documentation contains no dosing for children.
Contraindications – when the medicine must not be used
- allergy (hypersensitivity) to hymecromone or the excipients;
- obstruction of the bile ducts;
- acute liver and/or kidney failure;
- ulcerative colitis and Crohn’s disease.
Precautions and warnings
- Stop treatment if any symptoms of liver and/or kidney failure occur (e.g. yellowing of the skin, dark urine, reduced urination, swelling).
- Consult your doctor even if these conditions occurred in the past.
- Pain in the upper right abdomen with fever, jaundice, dark urine or pale stools is not a condition for self-treatment.
- The medicine contains less than 1 mmol (23 mg) sodium per tablet, i.e. it is essentially “sodium-free”.
Interactions with other medicines, alcohol and food
- Morphine reduces the activity of hymecromone.
- Metoclopramide – when used together, the activity of both medicines is reduced.
- Tell your doctor or pharmacist about all medicines you take.
- Take the medicine half an hour before meals.
Pregnancy and breastfeeding
There are no safety data for use in pregnancy; due to lack of human data the medicine should not be used during pregnancy. It is also not recommended during the entire breastfeeding period.
Driving and using machines
Mendiaxon has no influence on the ability to drive and use machines.
Possible side effects
Common (up to 1 in 10): diarrhoea.
Frequency not known: anaphylactic reactions including hives, itching, shortness of breath, angioedema and low blood pressure, which may lead to anaphylactic shock.
Overdose, missed dose and stopping treatment
There are no data on overdose of hymecromone. If you have taken more than you should, contact your doctor or pharmacist immediately.
If you forget a dose, take it straight away; do not take a double dose to make up for a missed one.
When to seek medical help immediately?
- difficulty breathing, swelling of the face, lips, tongue or throat, hives and itching all over the body, weakness (possible anaphylaxis);
- yellowing of the skin or eyes, dark urine, reduced urination;
- severe pain in the upper abdomen, especially with fever, chills or vomiting;
- blood in the stool or black stools, persistent bloody diarrhoea.
Pharmacist's advice
Mendiaxon is a medicine for short-term, symptomatic use in pain associated with indigestion. Take it half an hour before meals, and if there is no improvement after 7 days, do not extend treatment on your own – the cause of the symptoms needs to be established.
Smaller, more frequent meals and avoiding fatty, fried and heavy food and alcohol help alongside treatment. If you notice diarrhoea, drink enough fluids.
If you use metoclopramide (an anti-nausea medicine) or morphine-containing painkillers, tell your pharmacist – these medicines reduce the effect of hymecromone.
Availability and price
Mendiaxon 200 mg is a non-prescription medicine in Serbia, available only in pharmacies. This page is informative and is not an offer to buy the medicine online.
For current availability and price, please contact the pharmacy. The stronger form, Mendiaxon forte 400 mg, is a separate prescription-only medicine.
Composition, packaging and manufacturer
- Active substance: hymecromone, 200 mg per tablet.
- Excipients: potato starch; gelatin; sodium lauryl sulfate; magnesium stearate.
- Pack: carton with 3 PVC/aluminium blisters of 10 tablets (30 tablets).
- Marketing authorisation holder: Pharmanova d.o.o. Obrenovac, Industrijska 8. Manufacturer: Adamed Pharma S.A., ul. Marszałka Józefa Piłsudskiego 5, Pabianice, Poland.
- Authorisation renewed on 14.01.2025 (number 001339765 2024 59010 007 000 515 021 04 001).
Storage
- Keep out of the sight and reach of children.
- Store below 25 °C in the original package.
- Do not use after the expiry date.
- Return unused medicine to a pharmacy that collects pharmaceutical waste.
Frequently asked questions
What is Mendiaxon used for today?
According to the leaflet approved in January 2025, for the symptomatic treatment of pain associated with indigestion (dyspepsia) in adults, for no longer than 7 days without consulting a doctor.
When is Mendiaxon taken – before or after meals?
Half an hour before meals, 1 to 2 tablets three times daily. The tablets are not divided.
May I take Mendiaxon if I have gallstones?
Not without a doctor. The medicine is contraindicated in obstruction of the bile ducts, and pain due to gallstones requires medical assessment.
Is there a stronger Mendiaxon?
Yes, Mendiaxon forte 400 mg is a separate medicine with its own leaflet and is available on prescription. This page refers to Mendiaxon 200 mg, which is available without a prescription.
Related information
For additional care and support with digestive and bile complaints, see also the Bile and liver category – products in this category do not replace the medicine you have been prescribed.
Sources
- ALIMS – Package leaflet Mendiaxon 200 mg tablets (January 2025, in Serbian)
- ALIMS – Summary of Product Characteristics Mendiaxon 200 mg (in Serbian)
Sources checked on: 23 October 2026.
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Additional information
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Shipping cost
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