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Kventiax 25 mg, 100 mg and 200 mg film-coated tablets – quetiapine for schizophrenia and bipolar disorder
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- Stock: Zabrana online prodaje
- Brand: KRKA-EN
- Model: BR-2232036216
Kventiax film-coated tablets contain quetiapine (as quetiapine fumarate), a medicine from the antipsychotic group. It is used in adults to treat schizophrenia and bipolar disorder.
The medicine is available as film-coated tablets of 25 mg (light red), 100 mg (yellow-brown) and 200 mg (white), in packs of 60 tablets. Kventiax SR (prolonged-release tablets) is a separate form with different dosing and is not described on this page.
Important warning
- Prescription status: the medicine is dispensed on medical prescription (R).
- It must not be taken with certain HIV medicines, azole antifungals, erythromycin, clarithromycin or nefazodone. Do not drink grapefruit juice during treatment.
- In elderly people with dementia, medicines of this group increase the risk of stroke and death – Kventiax must not be used in these patients.
- Dizziness, drowsiness and a drop in blood pressure on standing are common (risk of falls); weight gain and increases in blood sugar and lipids are possible – regular check-ups are needed.
- This page is for information only and is not an offer to buy the medicine online.
What is Kventiax used for and how is it taken correctly?
Key facts about the medicine
| Name of the medicine | Kventiax® 25 mg, 100 mg and 200 mg film-coated tablets |
|---|---|
| Active substance | quetiapine (as quetiapine fumarate) |
| Strength | 25 mg; 100 mg; 200 mg |
| Pharmaceutical form | film-coated tablet |
| Therapeutic group | antipsychotics (diazepines, oxazepines, thiazepines and oxepines) |
| Pack | 60 film-coated tablets (6 blisters of 10) for each strength |
| Marketing authorisation holder / manufacturer | Krka-Farma d.o.o. Belgrade; manufacturers Krka d.d., Novo mesto, Slovenia and Krka-Farma d.o.o., Jastrebarsko, Croatia |
| Prescription status | R – on medical prescription |
What is Kventiax used for?
- schizophrenia;
- bipolar disorder: moderate to severe manic episodes, major depressive episodes and prevention of recurrence in patients whose manic or depressive episodes respond to quetiapine.
How is Kventiax taken and dosed?
Each indication has a different dosing regimen; the starting dose and gradual increase are set by the doctor. The maintenance dose is usually between 150 mg and 800 mg a day. The film-coated tablets are swallowed whole with enough water, with or without food, once a day at bedtime or twice a day – depending on the illness.
| Indication (adults) | Schedule | Dosing according to the SmPC |
|---|---|---|
| Schizophrenia | twice daily | total 50 mg (day 1), 100 mg (day 2), 200 mg (day 3), 300 mg (day 4); then usually 300–450 mg/day, range 150–750 mg/day |
| Manic episode of bipolar disorder | twice daily | 100 mg (day 1), 200 mg (day 2), 300 mg (day 3), 400 mg (day 4); increases of no more than 200 mg/day up to 800 mg on day 6; usually 400–800 mg/day |
| Depressive episode of bipolar disorder | once daily at bedtime | 50 mg (day 1), 100 mg (day 2), 200 mg (day 3), 300 mg (day 4); recommended 300 mg/day (200–600 mg in some patients) |
| Prevention of recurrence in bipolar disorder | twice daily | continue the dose that worked; range 300–800 mg/day, lowest effective dose |
Special patient groups
- Children and adolescents under 18: the medicine is not intended for this group.
- Elderly patients: slower titration and lower doses; efficacy in depressive episodes of bipolar disorder has not been established over 65 years.
- Liver impairment: treatment starts at 25 mg a day, increasing by 25–50 mg a day to an effective dose.
- Kidney impairment: no dose adjustment is needed.
Contraindications – when the medicine must not be used
- allergy to quetiapine or any of the excipients;
- concomitant use of certain HIV medicines, azole antifungals, erythromycin, clarithromycin or nefazodone.
Warnings and precautions
- heart disease, rhythm disorders or medicines affecting heart rhythm; low blood pressure; previous stroke;
- liver disease; seizures; diabetes or risk of diabetes (blood sugar monitoring);
- previous low white blood cell count; elderly with dementia or Parkinson’s disease; family history of blood clots; sleep apnoea;
- difficulty urinating, enlarged prostate, constipation or increased eye pressure; drug or alcohol abuse;
- suicidal thoughts and worsening depression, especially at the start of treatment and in people under 25;
- severe skin reactions (SJS, TEN, DRESS, AGEP) – stop the medicine and contact a doctor immediately;
- weight gain – monitor regularly; possible false-positive urine tests for methadone or tricyclic antidepressants; the medicine contains lactose.
Interactions with other medicines, food and drink
- contraindicated: certain HIV medicines, azole antifungals, erythromycin, clarithromycin, nefazodone;
- phenytoin, carbamazepine (antiepileptics); blood pressure medicines; barbiturates;
- thioridazine, lithium; medicines affecting heart rhythm or electrolyte balance (e.g. diuretics, certain antibiotics);
- medicines that cause constipation and anticholinergics;
- alcohol – increases drowsiness; grapefruit juice – do not drink during treatment.
Pregnancy and breast-feeding
- Pregnancy: do not take the medicine without first talking to your doctor. Newborns whose mothers took the medicine in the last trimester may show shaking, muscle stiffness or weakness, drowsiness, agitation, breathing and feeding problems.
- Breast-feeding: the medicine must not be taken while breast-feeding.
Driving and using machines
- The medicine may cause drowsiness – do not drive or operate machinery until you know how it affects you.
Possible side effects
- Very common: dizziness, headache, dry mouth, drowsiness, withdrawal symptoms on stopping, weight gain, abnormal muscle movements, changes in triglycerides and cholesterol.
- Common: fast heartbeat and palpitations, constipation, indigestion, weakness, swelling of arms and legs, low blood pressure on standing, high blood sugar, blurred vision, nightmares, increased appetite, irritability, speech disorder, suicidal thoughts, shortness of breath, vomiting, fever, thyroid hormone changes, reduced blood cell counts, increased liver enzymes and prolactin.
- Uncommon: seizures, allergic reactions, restless legs syndrome, difficulty swallowing, tardive dyskinesia, sexual dysfunction, diabetes, QT prolongation, slow heart rate, difficulty urinating, fainting, blocked nose, low sodium.
- Rare and very rare: neuroleptic malignant syndrome, jaundice and hepatitis, priapism, venous blood clots, pancreatitis, agranulocytosis, bowel obstruction, metabolic syndrome, severe skin and allergic reactions, rhabdomyolysis.
Overdose, missed dose and stopping treatment
- Overdose: drowsiness, dizziness and irregular heartbeat may occur – go to a doctor or the nearest hospital immediately and take the tablets with you.
- Missed dose: take it as soon as you remember; if it is nearly time for the next dose, wait until then. Do not take a double dose.
- Stopping treatment: abrupt stopping may cause insomnia, nausea, headache, diarrhoea, vomiting, dizziness and irritability; the doctor will advise gradual dose reduction over at least 1–2 weeks.
When to seek medical help immediately?
- high fever, muscle stiffness, sweating and altered consciousness (neuroleptic malignant syndrome);
- uncontrolled movements of the face or tongue; seizures; prolonged and painful erection;
- fast or irregular heartbeat at rest, chest pain, breathing difficulties or unexplained tiredness;
- fever, sore throat or other infection (possible very low white blood cell count);
- constipation with persistent abdominal pain; swelling, pain and redness of a leg or chest pain with breathing difficulty (blood clot);
- thoughts of self-harm or suicide; rash with blisters and peeling skin.
Pharmacist's advice
Do not stop Kventiax on your own even if you feel better – withdrawal symptoms and relapse are possible; the dose is reduced gradually in agreement with your doctor. At the start of treatment and when the dose is increased, get up slowly, especially at night.
Check your weight once a week and agree with your doctor on blood sugar and lipid tests. Dry mouth is very common – drink water and use mouth-moisturising products. Do not drink grapefruit juice and do not take St John’s wort or new medicines without checking with a pharmacist.
Availability and price
This page is for information only. Kventiax is a prescription-only medicine and ApotekaOnline.rs does not offer it for online purchase.
Check availability and dispensing conditions at a pharmacy with your doctor’s prescription.
Related information
Kventiax is used under the supervision of a psychiatrist, with regular checks of body weight, blood sugar and blood lipids. For questions about treatment, contact the doctor in charge; always read the enclosed leaflet.
Composition, pack and manufacturer
- Active substance: quetiapine 25 mg, 100 mg or 200 mg per film-coated tablet (as quetiapine fumarate).
- Excipients: core – lactose monohydrate, calcium hydrogen phosphate dihydrate, microcrystalline cellulose, povidone, sodium starch glycolate (type A), magnesium stearate; coating – hypromellose, titanium dioxide (E171), macrogol 4000; colours – 25 mg: yellow and red iron oxide (E172), 100 mg: yellow iron oxide (E172).
- Appearance: 25 mg – round light red film-coated tablets with bevelled edges; 100 mg – round yellow-brown; 200 mg – round white.
- Pack: 60 film-coated tablets (6 PVC/Al blisters of 10).
- Marketing authorisation holder: Krka-Farma d.o.o. Belgrade; manufacturers: Krka d.d., Novo mesto, Slovenia; Krka-Farma d.o.o., Jastrebarsko, Croatia.
- Authorisation numbers (renewal 22.02.2022): 25 mg – 515-01-01306-20-001; 100 mg – 515-01-01307-20-001; 200 mg – 515-01-01308-20-001.
Storage
- The medicine does not require any special storage conditions.
- Keep out of the sight and reach of children.
- Do not use after the expiry date; return unused medicine to a pharmacy that collects unused medicines.
Frequently asked questions
Is Kventiax taken once or twice a day?
It depends on the illness: for depressive episodes of bipolar disorder once a day at bedtime, and for schizophrenia, mania and prevention of recurrence twice a day. The schedule is set by the doctor.
Why must I not drink grapefruit juice with Kventiax?
The leaflet states that grapefruit juice may affect how the medicine works, so it must not be drunk during treatment.
Does Kventiax affect body weight?
Weight gain is a very common side effect. You and your doctor should monitor your weight regularly, and the doctor may also check blood sugar and lipids.
What is the difference between Kventiax and Kventiax SR?
Kventiax are immediate-release film-coated tablets (25, 100 and 200 mg), while Kventiax SR are prolonged-release tablets. They are different forms and the dosing of one must not be transferred to the other without a doctor.
Sources
- ALIMS – Package leaflet Kventiax 25 mg, 100 mg and 200 mg (PIL, Serbian)
- ALIMS – Summary of product characteristics Kventiax 25 mg (SmPC, Serbian)
- ALIMS – Summary of product characteristics Kventiax 100 mg (SmPC, Serbian)
Date sources were checked: 25.10.2026.
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Additional information
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