Fluimucil 100 mg/5 mL oral solution – acetylcysteine for thick mucus and easier coughing up

Fluimucil oral solution contains acetylcysteine, a mucolytic – an expectorant medicine that thins thick, sticky mucus and helps clear it from the airways.

Each 5 mL of solution contains 100 mg acetylcysteine. The solution is clear, raspberry-flavoured and supplied in a 100 mL glass bottle with a graduated measuring cup. According to the ALIMS list of medicines with a changed name (05–07/2026), this form has been called Fluimucil® za decu (“for children”) since 2026 (same authorisation, same composition). Fluimucil 100 mg and 200 mg granules and Fluimucil 600 mg effervescent tablets are separate medicines with their own leaflets.

What is Fluimucil oral solution used for and how should it be dosed correctly?

Key facts about the medicine

What is Fluimucil oral solution used for?

According to the package leaflet, Fluimucil oral solution is used to treat respiratory disorders with excessive production of thick, viscous mucus in children from 2 years of age, adolescents and adults.

If symptoms persist or worsen after 5–10 days, a doctor should be consulted.

How is it taken and dosed?

Shake the bottle before use. Measure the dose with the measuring cup provided. Recommended doses according to the leaflet:

• Treatment lasts 5 to 10 days; treatment longer than 10 days must be prescribed by a doctor.
• After first opening, the bottle can be used for 10 days (stored below 25 °C).
• Mixing other medicines with the oral solution is not recommended.
• A faint sulphur smell is typical of acetylcysteine and does not mean the medicine has changed.

Special patient groups

• Children: the medicine is intended for children from 2 years of age; it must not be used in younger children, who because of the structure of their airways cannot cough up the thinned mucus effectively.
• Older people and people with a weak cough: people with reduced respiratory function and a reduced ability to cough up mucus should consult a doctor before use; if needed, respiratory physiotherapy (postural drainage, suction of secretions) is used together with the medicine.

Contraindications – when the medicine must not be used

Do not take Fluimucil oral solution:

• if you are allergic to acetylcysteine or any of the ingredients;
• if you are pregnant or breast-feeding (self-medication; see the pregnancy section);
• in children under 2 years.

Warnings and precautions

Use the medicine with caution and under medical supervision if you or your child:

• have bronchial asthma – stop treatment immediately and see a doctor if breathing difficulty, bronchospasm or worsening of the disease occurs;
• have or have had a stomach or duodenal ulcer, or take medicines that damage the stomach;
• have histamine intolerance (hypersensitivity reactions are possible).

At the start of treatment the mucus may become thinner and increase in volume. Acetylcysteine can affect some blood and urine tests (salicylates, ketone bodies) – tell your doctor you are taking it before laboratory tests. The solution contains sodium (19.1 mg per 5 mL; 38.2 mg per 10 mL), sodium benzoate, methyl parahydroxybenzoate (may cause allergic reactions, possibly delayed), propylene glycol and small amounts of ethanol (38.5 mg per 100 mL).

Interactions with other medicines, food and drink

Tell your doctor or pharmacist about all medicines you take. According to the leaflet:

• antitussives (cough suppressants) – do not take at the same time because of possible mucus build-up;
• antibiotics – take them separately from Fluimucil, at least 2 hours apart (does not apply to loracarbef);
• activated charcoal – may reduce the effect of the medicine;
• nitroglycerin – taking both may cause a marked drop in blood pressure and headache.

Pregnancy and breast-feeding

• Pregnancy and breast-feeding: do not take the medicine on your own initiative. If you are pregnant or breast-feeding, Fluimucil may be taken only if prescribed by a doctor and under direct medical supervision.

Driving and using machines

Fluimucil has no effect on the ability to drive and use machines.

Possible side effects

According to the leaflet, the following may occur:

• uncommon (up to 1 in 100 people): allergic reactions, headache, ringing in the ears, fast heartbeat, vomiting, diarrhoea, inflammation of the mouth lining, stomach pain, nausea, hives, rash, angioedema (swelling of the face, lips, throat or tongue), itching, fever, drop in blood pressure;
• rare (up to 1 in 1,000): bronchospasm, shortness of breath, indigestion;
• very rare (up to 1 in 10,000): severe allergic reaction (anaphylactic shock), bleeding;
• frequency not known: bronchial obstruction, facial swelling.

Very rare cases of serious skin reactions (Stevens-Johnson and Lyell syndromes) have been reported. If any changes in the skin or mucous membranes occur, or if bleeding time is prolonged, stop using the medicine and see your doctor.

Overdose, missed dose and stopping treatment

• Overdose: nausea, vomiting and diarrhoea may occur. If you have accidentally taken the medicine or a larger dose, tell your doctor immediately or go to the nearest hospital.
• Missed dose: do not take a double dose to make up for a missed one.
• Duration and stopping: treatment lasts 5–10 days; if symptoms persist, recur more often or worsen, see your doctor.

Related information

For additional care and support during colds, see also the category Common cold – products in this category do not replace the medicine. Do not take cough-suppressing products with Fluimucil without advice from a doctor or pharmacist.

Composition, pack and manufacturer

• Active substance: acetylcysteine – 100 mg per 5 mL oral solution.
• Excipients: methyl parahydroxybenzoate (E218); sodium benzoate; disodium edetate; sodium carboxymethylcellulose; saccharin sodium; sodium cyclamate; sucralose; raspberry flavour (contains ethanol and propylene glycol); sodium hydroxide; purified water.
• Pack: amber glass bottle with 100 mL solution, tamper-evident cap, graduated measuring cup and leaflet.
• Marketing authorisation holder: Bonifar d.o.o. Novi Beograd, Bulevar Zorana Đinđića 64a. Manufacturer: Zambon S.p.A., Vicenza, Italy.

Storage

• The medicine does not require any special storage conditions.
• After first opening, use within 10 days, stored below 25 °C.
• Keep out of the sight and reach of children; do not use after the expiry date.

Frequently asked questions

From what age can Fluimucil oral solution be given?

From 2 years of age. Children over 2 take 5 mL (100 mg) 2–4 times a day depending on age, and adults 10 mL (200 mg) 2–3 times a day. It must not be given to children under 2.

Can Fluimucil be combined with a dry-cough syrup?

No. The leaflet states that acetylcysteine should not be taken with antitussives (cough suppressants), because the thinned mucus may build up in the airways when the cough reflex is suppressed.

How long can an opened bottle be used?

After first opening the solution can be used for 10 days if stored below 25 °C.

Why does the solution smell slightly of sulphur?

A faint sulphur smell is typical of the active substance acetylcysteine and does not indicate any change in the medicine.

Sources

• ALIMS – Summary of Product Characteristics, Fluimucil® 100 mg/5 mL oral solution (SmPC, Serbian)
• ALIMS – Package leaflet, Fluimucil® 100 mg/5 mL oral solution (PIL, Serbian)

Sources checked on: 25 October 2026.