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Fervex for children 280 mg/10 mg/100 mg granules – cold and rhinopharyngitis in children from 6 years
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- Stock: Zabrana online prodaje
- Brand: BRISTOL MYERS SQUIBB
- Model: BR-0550
Fervex for children, 280 mg/10 mg/100 mg, granules for oral solution is a combination medicine with three active substances: paracetamol (against pain and fever), pheniramine maleate (an antihistamine that reduces runny nose, sneezing and watery eyes) and ascorbic acid (vitamin C).
It is dissolved in water and used in children over 6 years, adolescents and adults weighing 50 kg or less for short-term relief of cold symptoms. The pack contains 8 sachets.
Important warning
- Supply status in Serbia: available without a prescription.
- The medicine contains paracetamol – do not combine it with other medicines containing paracetamol or antihistamines without medical advice; overdose can be fatal.
- Treatment must not last longer than 3 days; not for children under 6 years.
- The medicine may cause drowsiness – avoid alcohol and take care when driving.
- Use the medicine only as described in the official leaflet and as advised by a doctor or pharmacist.
- This page is for information only and is not an offer to buy the medicine online.
What is Fervex for children used for and how should it be taken?
Key facts about the medicine
| Name of the medicine | Fervex for children, 280 mg/10 mg/100 mg, granules for oral solution |
|---|---|
| Active substance | paracetamol, pheniramine maleate, ascorbic acid (vitamin C) |
| Strength | 280 mg paracetamol, 10 mg pheniramine maleate and 100 mg ascorbic acid per sachet |
| Pharmaceutical form | granules for oral solution (sachet) |
| Therapeutic group | analgesics; anilides, combinations (ATC N02BE51) |
| Pack | 8 sachets (paper/aluminium/polyethylene) |
| Marketing authorisation holder | Amicus SRB d.o.o., Belgrade |
| Supply status (Serbia) | available without a prescription |
What is Fervex for children used for?
To relieve symptoms of colds and inflammation of the nasal and throat lining (rhinopharyngitis) in children over 6 years, adolescents and adults weighing 50 kg or less, with:
- clear runny nose and watery eyes
- sneezing
- headache and/or fever
How is it used and dosed?
The dose depends on the child's body weight:
| 21–25 kg (children 6–10 years) | 1 sachet; at least 12 hours apart; maximum 2 sachets a day (560 mg paracetamol, 20 mg pheniramine, 200 mg vitamin C) |
|---|---|
| 26–40 kg (children 10–12 years) | 1 sachet; at least 8 hours apart; maximum 3 sachets a day (840 mg paracetamol, 30 mg pheniramine, 300 mg vitamin C) |
| 41–50 kg (children 12–15 years, adolescents and adults up to 50 kg) | 1 sachet; at least 6 hours apart; maximum 4 sachets a day (1120 mg paracetamol, 40 mg pheniramine, 400 mg vitamin C) |
- The total daily dose of paracetamol must not exceed 60 mg/kg body weight.
- Dissolve the contents of the sachet in a sufficient amount of warm or cold water and drink.
- One sachet is one dose; the minimum intervals between doses are given in the table.
- Treatment must not last longer than 3 days.
Check whether other medicines you take (including non-prescription ones) contain paracetamol, pheniramine or vitamin C, to avoid overdose.
Special patient groups
- Children under 6 years: must not be used.
- In children the total daily dose of paracetamol must not exceed 60 mg/kg/day; combined use with another fever medicine may only be prescribed by a doctor.
- Kidney or liver disease: consult a doctor before use.
Contraindications – when the medicine must not be used
- allergy to the active substances or any excipient
- children under 6 years
- closed-angle glaucoma (raised pressure in the eye)
- difficulty passing urine due to prostate or other disorders
- severe liver disease
The medicine should not be taken during pregnancy and breastfeeding unless prescribed by a doctor.
Precautions and warnings
- See a doctor in case of purulent nasal discharge, persistent fever, pain lasting more than 3 days or no improvement after 3 days.
- Consult a doctor or pharmacist before use if you have kidney or liver disease, misuse alcohol, have an eating disorder or are dehydrated, or have acute viral hepatitis.
- Vitamin C should be used with caution in disorders of iron metabolism or glucose-6-phosphate dehydrogenase deficiency.
- Paracetamol can cause serious skin reactions – stop the medicine immediately and see a doctor if a rash or any other sign of allergy appears.
- Contains no sugar; contains the sweetener acesulfame potassium.
- Contains the azo dyes Sunset yellow FCF (E110) and Allura red AC (E129), which may cause allergic reactions.
- Contains less than 1 mmol (23 mg) sodium per sachet.
Interactions with other medicines, alcohol and food
- Oral anticoagulants (blood thinners): at high doses the medicine increases their effect; the doctor may adjust the dose.
- Flucloxacillin (antibiotic): increased risk of metabolic acidosis, especially in severe kidney impairment, sepsis, malnutrition and chronic alcoholism.
- Other medicines containing antihistamines or paracetamol: do not combine without medical advice.
- Laboratory tests: tell the doctor you are taking the medicine if you have uric acid or blood sugar tests.
- Alcohol: increases drowsiness; do not drink alcohol during treatment, and it is preferable to start treatment in the evening.
Pregnancy and breastfeeding
Use during pregnancy is not recommended; if necessary, the lowest effective dose is used for the shortest time, on medical advice. Use during breastfeeding is not recommended. Paracetamol may affect female fertility; this effect is reversible after stopping treatment.
Driving and using machines
The medicine may cause drowsiness or reduced alertness, especially at the start of treatment. The risk increases with alcohol, medicines containing alcohol or sedative medicines – take care when driving or operating machines.
Possible side effects
Related to paracetamol:
- rare (up to 1 in 1,000): rash, redness or an allergic reaction with sudden swelling of the face and neck or sudden weakness with low blood pressure – stop treatment, see a doctor and never take paracetamol-containing medicines again
- very rare (up to 1 in 10,000): serious skin reactions – same action
- very rare: low platelet or white blood cell counts (nosebleeds or bleeding gums); clotting disorders have also been reported
Related to pheniramine:
- drowsiness or reduced attention, more pronounced at the start of treatment
- dry mouth, constipation, visual disturbances, palpitations, urinary retention
- drop in blood pressure on standing with dizziness; balance problems, impaired memory or concentration (more common in the elderly)
- impaired coordination, tremor, confusion, hallucinations; less often agitation, nervousness, insomnia
- rarely hypersensitivity reactions (itching, urticaria, swelling, Quincke's oedema, anaphylactic shock) and blood count changes
Suspected side effects can be reported to a doctor, pharmacist or ALIMS.
Overdose, missed dose and stopping treatment
- Overdose: stop treatment and contact a doctor or emergency service immediately – overdose can be fatal.
- Missed dose: do not take a double dose to make up for a missed one.
- Stopping treatment: the leaflet describes no special measures; the medicine is used short-term.
When to seek medical help immediately?
- more medicine than recommended has been taken, or another paracetamol-containing medicine at the same time – even without symptoms
- rash, swelling of the face, lips or throat, difficulty breathing or sudden weakness
- nosebleeds or bleeding gums, unexplained bruising
- confusion, hallucinations or inability to pass urine
- purulent nasal discharge, high fever for more than 3 days or worsening condition
Pharmacist's advice
Fervex for children is dosed by body weight, not only by age – weigh the child before the first dose and check the right row in the table. For younger children the minimum interval between sachets is as long as 12 hours.
Before giving it, check whether the child is already receiving a syrup or suppositories with paracetamol, or an allergy syrup – the combination can lead to overdose. As the medicine may cause drowsiness, the first dose is best given in the evening.
Availability and price
The medicine is available without a prescription, but under the regulations of the Republic of Serbia it cannot be ordered online. This page is for information only.
Please contact a pharmacy to check availability.
Related information
For additional care and support with colds in children, see also the Colds in children category – products in this category do not replace the medicine you have been prescribed.
Composition, packaging and manufacturer
- One sachet contains 280 mg paracetamol, 10 mg pheniramine maleate and 100 mg ascorbic acid.
- Excipients: mannitol, anhydrous citric acid, povidone, anhydrous magnesium citrate, acesulfame potassium, raspberry flavour (contains azo dyes E110 and E129).
- Appearance: granulated powder, pale to dark pink; pink solution after dissolving.
- Pack: carton with 8 sachets and a leaflet.
- Marketing authorisation holder: Amicus SRB d.o.o., Milorada Jovanovića 9, Belgrade. Manufacturer: UPSA SAS, Agen / Le Passage, France.
Storage
- No special storage conditions.
- Keep out of the sight and reach of children; do not use after the expiry date.
- Return unused medicine to a pharmacy that collects unused medicines; do not dispose of it via wastewater or household waste.
Frequently asked questions
From what age can Fervex for children be given?
From 6 years. It is intended for children over 6 years, adolescents and adults weighing up to 50 kg; the dose and interval between sachets depend on body weight.
How many sachets of Fervex for children may a 25 kg child take per day?
According to the leaflet table, a child weighing 21 to 25 kg takes 1 sachet at least 12 hours apart, with a maximum of 2 sachets a day.
Is Fervex for children sugar-free?
Yes. It contains no sugar but the sweetener acesulfame potassium; it does contain the azo dyes E110 and E129, which may cause allergic reactions.
How long can Fervex for children be given?
For a maximum of 3 days. If the child does not feel better or feels worse after 3 days, contact a doctor.
Sources
- ALIMS – Patient leaflet Fervex for children, 280 mg/10 mg/100 mg, granules for oral solution (authorisation 515-01-04198-21-001 of 21.07.2022, approved July 2022)
- ALIMS – Summary of product characteristics Fervex for children, 280 mg/10 mg/100 mg, granules for oral solution
Date sources were checked: 23 October 2026.
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