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Cinnarizine (Cinarizin) – medicine for vertigo, tinnitus and peripheral circulation; in Serbia as Cinedil 75 mg
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- Stock: Zabrana online prodaje
- Brand: OSTALO
- Model: BR-60551005162
Cinnarizine (Serbian: cinarizin) is the name of an active substance from the group of anti-vertigo medicines. It works in two ways: it blocks calcium entry into the smooth muscle cells of blood vessels, preventing them from contracting, and it has an antihistamine effect. This is why it calms symptoms of inner ear and balance (vestibular) disorders and helps in some peripheral circulation disorders.
Cinnarizine is not a brand name. In Serbia one cinnarizine medicine is currently registered – Cinedil 75 mg tablets (Alkaloid), available on prescription. The information on this page therefore comes from the official leaflet and summary of product characteristics of that medicine.
Important warning
- Supply status in Serbia: the cinnarizine medicine (Cinedil 75 mg) is prescription-only.
- Cinnarizine may cause drowsiness and slower reflexes, especially at the start of treatment; with alcohol, sedatives, sleeping pills and some antidepressants drowsiness is more pronounced.
- Must not be taken with extrapyramidal symptoms (movement disorders), after a recent heart attack, during pregnancy or while breastfeeding.
- The 75 mg tablets are not recommended for children.
- This page is for information only and is not an offer to buy the medicine online.
What is cinnarizine, which complaints is it used for and what should you watch out for?
Basic information about the medicine
| Active substance | cinnarizine |
|---|---|
| Registered medicine in Serbia | Cinedil®, 75 mg, tablets |
| Strength | 75 mg cinnarizine per tablet |
| Pharmaceutical form | tablet – white, round, biconvex, with a score line (not intended for breaking) |
| Therapeutic group | antivertigo preparations (ATC N07CA02) |
| Pack | 45 tablets (3 blisters of 15) |
| Marketing authorisation holder / manufacturer | ALKALOID D.O.O. BEOGRAD; manufacturer: ALKALOID AD Skopje, North Macedonia |
| ALIMS licence number | 000457630 2023 of 21.02.2024 (licence renewal) |
| Supply status | prescription-only medicine |
Which complaints is cinnarizine used for?
- vestibular disorders – vertigo, ringing in the ears (tinnitus), nausea and vomiting, similar to those seen in Ménière’s disease;
- adjunctive treatment of symptoms of peripheral circulation disorders: Raynaud’s syndrome (pale, cold fingers due to vessel spasm), intermittent claudication (leg pain when walking) and cold extremities in vasospastic disorders.
Vertigo and ringing in the ears can have different causes – the cause should be established by a doctor before treatment.
Dosing of cinnarizine (Cinedil 75 mg)
The medicine is taken by mouth by adults and older people. Doses for older people are the same as for adults.
| Purpose | Dose according to the leaflet |
|---|---|
| Vestibular disorders – initial | 75 mg (1 tablet) once or twice daily |
| Peripheral circulation disorders – initial | 75 mg (1 tablet) two to three times daily |
| Maintenance | 75 mg (1 tablet) once daily |
| Maximum daily | 225 mg (3 tablets) |
Taking it after meals may reduce stomach discomfort. This is general dosing – the dose and duration are set by your doctor.
Special patient groups
- Children: the 75 mg tablets are not recommended for children.
- Older people: a fall in body temperature (hypothermia) and movement disorders (extrapyramidal symptoms) may occur.
- Kidney or liver failure: talk to your doctor before use.
Contraindications – when cinnarizine must not be used
- allergy to cinnarizine or the excipients (rash, itching, swelling of the face or lips, shortness of breath);
- extrapyramidal symptoms (tremor, stiffness, involuntary movements);
- a recent heart attack;
- pregnancy and breastfeeding.
Precautions and warnings
- Talk to your doctor if you have kidney or liver failure, porphyria, Parkinson’s disease or low blood pressure.
- Cinnarizine may give false-negative results in allergy skin tests – stop the medicine at least 4 days before testing.
- Contains less than 1 mmol sodium per dose, i.e. essentially “sodium-free”.
Interactions with other medicines and alcohol
- Anti-anxiety medicines, sleeping pills and certain antidepressants: increased drowsiness.
- Alcohol: reduces psychophysical abilities – avoid during treatment.
- Medicines that can cause extrapyramidal syndrome (neuroleptics, metoclopramide, reserpine, methyldopa): do not take at the same time.
- Other calcium channel blockers: cinnarizine increases their effect; vasodilator medicines increase the vasoactive effect of cinnarizine.
- Domperidone: synergistic effect.
Pregnancy and breastfeeding
According to the contraindications in the leaflet, cinnarizine must not be taken during pregnancy or while breastfeeding. If you are pregnant, think you may be pregnant or are breastfeeding, ask your doctor before any treatment.
Driving and using machines
Especially at the start of treatment cinnarizine may cause drowsiness and prolong reaction time, which is important for drivers and machine operators.
Possible side effects
- Common: drowsiness, nausea, weight gain, indigestion.
- Uncommon: marked lethargy and sleepiness, tiredness, upper abdominal pain, vomiting, increased sweating, rash.
- Frequency not known: abnormal movements (trembling of hands and fingers, twisting of the body, difficulty walking, muscle stiffness), jaundice, a rash known as subacute cutaneous lupus erythematosus.
Report suspected side effects to your doctor, pharmacist or ALIMS.
Overdose, missed dose and stopping treatment
- Overdose: contact a doctor or emergency service immediately. Vomiting, drowsiness up to impaired consciousness and coma, hypotonia and movement disorders may occur; according to the SmPC, symptoms are mainly due to the anticholinergic effect, and seizures have been reported in small children. There is no specific antidote.
- Missed dose: do not take the missed dose – take the next one at the usual time and continue as scheduled. Do not take a double dose.
When to seek medical help immediately?
- trembling, muscle stiffness, involuntary body movements or difficulty walking
- yellowing of the skin or eyes
- swelling of the face or lips, shortness of breath, itchy rash
- severe drowsiness, confusion or loss of consciousness (especially if several tablets were taken or swallowed by a child)
- sudden severe dizziness with headache, weakness of an arm or leg, speech or vision disturbance
Pharmacist's advice
With vertigo it is important to get up slowly and take care not to fall, especially in older people. Because cinnarizine causes drowsiness in some people and the leaflet advises caution in low blood pressure, check how you react during the first days and measure your blood pressure if you tend to have low values.
In Raynaud’s syndrome and cold extremities the medicine is only an adjunctive treatment – keep your hands and feet warm. If you notice trembling hands, stiffness or a less steady gait, see your doctor, as these may be side effects on movement. Do not combine the medicine with alcohol or sleep aids without asking your pharmacist.
Availability and price
Cinnarizine (Cinedil 75 mg) is a prescription-only medicine and cannot be ordered online – this page is for information only.
Please check availability and supply conditions at a pharmacy.
Related information
For additional support with vertigo, see also the category Vertigo – products from this category do not replace the medicine prescribed for you; ask your pharmacist before combining circulation products with cinnarizine.
Composition, pack and manufacturer
- Active substance: cinnarizine 75 mg per tablet.
- Excipients: calcium hydrogen phosphate dihydrate; microcrystalline cellulose; colloidal anhydrous silica; sodium lauryl sulfate; magnesium stearate.
- Pack: carton with 3 PVC/Al blisters of 15 tablets (45 tablets).
- Marketing authorisation holder: ALKALOID D.O.O. BEOGRAD, Prahovska 3, Belgrade. Manufacturer: ALKALOID AD Skopje, Bulevar Aleksandar Makedonski 12, Skopje, North Macedonia.
Storage
- No special storage conditions.
- Keep out of the sight and reach of children.
- Shelf life: 3 years.
Frequently asked questions
Under which name is cinnarizine available in Serbia?
According to the ALIMS register, the registered medicine is Cinedil 75 mg tablets (Alkaloid). It is available on prescription.
Does cinnarizine help with ringing in the ears?
Ringing in the ears (tinnitus) is listed among the vestibular symptoms for which the medicine is approved, together with vertigo, nausea and vomiting. Because tinnitus has various causes, the doctor decides on its use.
Is cinnarizine also used for circulation in the legs?
Yes, as adjunctive treatment of symptoms of peripheral circulation disorders – Raynaud’s syndrome, leg pain when walking (intermittent claudication) and cold extremities. The usual dose is 1 tablet two to three times daily, as advised by a doctor.
Can I drink alcohol while taking cinnarizine?
It is not recommended. The combination of cinnarizine and alcohol increases drowsiness and reduces psychophysical abilities.
Sources
- ALIMS – Package leaflet Cinedil®, 75 mg, tablets (cinnarizine, February 2024, Serbian)
- ALIMS – Summary of product characteristics Cinedil®, 75 mg, tablets (Serbian)
Date sources were checked: 25 October 2026.
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