-150x150w.webp)
-150x150w.webp)
ASPIRIN PLUS C 400 mg/240 mg effervescent tablets – pain and fever with colds
Pogledajte blok ispod gde možete pronaći proizvode koji su slični ili imaju slična dejstva kao proizvod na čijoj se stranici nalazite.
- Stock: Zabrana online prodaje
- Brand: BAYER SCHERING PHARMA AG.
- Model: BR-15472
Aspirin plus C 400 mg/240 mg are effervescent tablets containing two active substances: acetylsalicylic acid (400 mg), which relieves pain, lowers fever and has an anti-inflammatory effect, and ascorbic acid (vitamin C, 240 mg). According to the approved leaflet, the medicine is intended for people aged 16 years and over.
It is used for mild to moderate pain such as headache, toothache, period pain and pain accompanying a cold (sore throat, aching limbs), as well as for fever. The tablet is dissolved in a glass of water before use.
Important warning
- Supply status in Serbia: available without a prescription (according to the leaflet approved by ALIMS).
- The medicine must not be given to children and adolescents under 16 years (risk of Reye's syndrome with viral infections).
- Do not take it if you have a stomach or intestinal ulcer, a bleeding tendency, take oral anticoagulants or are in the third trimester of pregnancy.
- Without medical advice, do not take it for more than 3 days for fever or more than 3 to 4 days for pain.
- Each effervescent tablet contains 466.4 mg of sodium – important for people on a low-salt diet.
- This page is for information only and is not an offer to buy the medicine online.
What is Aspirin plus C used for and how should the effervescent tablets be taken?
Key facts about the medicine
| Name of the medicine | Aspirin® plus C, 400 mg/240 mg, effervescent tablets |
|---|---|
| Active substance | acetylsalicylic acid + ascorbic acid (vitamin C) |
| Strength | 400 mg acetylsalicylic acid and 240 mg ascorbic acid per tablet |
| Pharmaceutical form | effervescent tablet |
| Therapeutic group | analgesics – other analgesics and antipyretics (ATC N02BA51) |
| Pack | 10 effervescent tablets (5 strips of 2) or 20 effervescent tablets (10 strips of 2) |
| Marketing authorisation holder | Bayer d.o.o. Beograd |
| Supply status (Serbia) | available without a prescription |
What is Aspirin plus C used for?
According to the patient leaflet and the summary of product characteristics, Aspirin plus C is used in people aged 16 years and over for:
- mild to moderate pain: headache, toothache, period pain
- pain associated with colds (headache, sore throat, aching limbs)
- fever (febrile conditions)
The vitamin C it contains replaces ascorbic acid, whose level in the body decreases during colds and flu.
How is it taken and dosed?
Usual dosage according to the leaflet, unless your doctor prescribes otherwise:
| Age | Single dose | Interval between doses | Maximum per day |
|---|---|---|---|
| 16 years and over | 1–2 effervescent tablets | 4–8 hours, no more than 3 times a day | 6 tablets |
| 65 years and over | 1 effervescent tablet | 4–8 hours | 5 tablets |
| under 16 years | must not be used | – | – |
- Method: dissolve the tablet in a glass of water and drink.
- Do not take on an empty stomach.
- Duration without medical advice: no more than 3 days for fever or 3–4 days for pain.
- If symptoms do not improve or get worse, see a doctor.
Special patient groups
- Children and adolescents under 16: the medicine must not be used (the only exception is the special indication of preventing thrombosis during heart surgery, decided by a doctor).
- Elderly (65+): the single dose is 1 tablet, no more than 5 tablets per day.
- Kidney or liver impairment: severe impairment is a contraindication; in milder impairment use only after advice from a doctor and pharmacist.
Contraindications – when the medicine must not be used
- hypersensitivity to acetylsalicylic acid, other salicylates, ascorbic acid or any of the excipients
- asthma or an allergic reaction (itching, angioedema, severe nasal inflammation, shock) previously caused by acetylsalicylic acid or other non-steroidal anti-inflammatory drugs (NSAIDs)
- stomach or intestinal ulcer
- bleeding or an increased risk of bleeding
- severe kidney, liver or heart impairment
- concomitant methotrexate at a dose of 15 mg per week or more
- concomitant oral anticoagulants
- third trimester of pregnancy (after week 24)
- current or previous kidney stones and increased oxalic acid in the urine
- haemochromatosis (iron storage disease)
- children and adolescents under 16 years
Precautions and warnings
- Do not combine with other medicines containing acetylsalicylic acid – risk of overdose.
- Regular use of painkillers, especially combinations of several painkillers, can permanently damage kidney function.
- If headaches persist despite high doses of painkillers, do not increase the dose – consult a doctor.
- Caution in G6PD deficiency, a history of ulcer, bleeding or gastritis, asthma, kidney or liver impairment and heavy menstrual bleeding.
- Acetylsalicylic acid increases the tendency to bleed even at low doses and for several days after intake – tell your doctor or dentist before any surgical or dental procedure.
- The medicine alters uric acid levels in the blood, which is relevant in gout.
- In children with a viral illness (flu, chickenpox) there is a risk of Reye's syndrome.
Interactions with other medicines, alcohol and food
The medicine must not be taken with methotrexate above 15 mg per week, or with oral anticoagulants in people who have or have had an ulcer. Always consult a doctor or pharmacist before use if you take:
- oral anticoagulants, heparins, thrombolytics, clopidogrel or ticlopidine
- other NSAIDs (medicines for pain and inflammation)
- glucocorticoids at high doses
- medicines for gout (benzbromarone, probenecid)
- diuretics, ACE inhibitors and angiotensin II antagonists (blood pressure medicines)
- methotrexate up to 15 mg per week, pemetrexed, anagrelide, deferasirox
- SSRI antidepressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline)
- antacids, gastrointestinal medicines and medicinal charcoal
- deferoxamine (because of vitamin C – possible effect on heart function)
The medicine may affect some laboratory tests (glucose, uric acid, creatinine, faecal occult blood test). Do not take on an empty stomach.
Pregnancy and breastfeeding
In the first five months of pregnancy the medicine should only be used on a doctor's advice. From the beginning of the sixth month of pregnancy (after week 24) it must not be taken, as it can seriously harm the mother and the baby.
The medicine passes into breast milk and, as a precaution, is not recommended during breastfeeding. Acetylsalicylic acid may temporarily reduce fertility in women.
Driving and using machines
According to the leaflet, the medicine has no effect on the ability to drive or use machines.
Possible side effects
For most side effects the frequency is not known. The leaflet lists:
- bleeding (nosebleeds, bleeding gums, small red spots on the skin), bleeding in the digestive tract (more common at higher doses), rarely bleeding in the brain
- stomach pain, diarrhoea, nausea and vomiting
- allergic reactions: rash, itching, asthma attack, swelling of the face with difficulty breathing, allergic shock
- headache, dizziness, ringing in the ears and a feeling of reduced hearing (usually a sign of overdose)
- raised liver enzymes, liver damage
- Reye's syndrome in children with a viral infection
Suspected side effects can be reported to your doctor, pharmacist or the Medicines and Medical Devices Agency of Serbia (ALIMS).
Overdose, missed dose and stopping treatment
- Overdose: ringing in the ears, a feeling of hearing loss, headache and dizziness. Stop taking the medicine and contact a doctor immediately.
- Missed dose: do not take a double dose to make up for a missed one.
- Stopping: take the medicine only while symptoms last; stop immediately in case of digestive tract bleeding or an allergic reaction.
When to seek medical help immediately?
- black or bloody stools, vomiting blood or bleeding in the mouth
- swelling of the face, lips or throat, difficulty breathing, an asthma attack or a severe skin reaction
- severe headache, ringing in the ears and hearing loss with dizziness (possible overdose)
- in a child or adolescent who has taken the medicine: vomiting, drowsiness, confusion or unusual behaviour
Pharmacist's advice
Before taking it, check whether other cold and flu medicines you are already using contain acetylsalicylic acid – taking them together can lead to overdose. Dissolve the tablet completely in a glass of water and do not take it on an empty stomach.
Because of the high sodium content (466.4 mg per tablet), people with high blood pressure or on a low-salt diet should ask a pharmacist for advice. For children and adolescents under 16, ask a doctor or pharmacist about a suitable medicine.
Availability and price
The medicine is available without a prescription but cannot be ordered online. This page is for information only.
Please contact a pharmacy to check availability and dispensing conditions.
Composition, packaging and manufacturer
- Each effervescent tablet contains 400 mg acetylsalicylic acid and 240 mg ascorbic acid.
- Excipients: sodium dihydrogen citrate, sodium hydrogen carbonate, citric acid, sodium carbonate.
- Appearance: white effervescent tablet marked "Bayer" on one side.
- Pack: 5 or 10 strips (aluminium/paper) of 2 tablets – 10 or 20 effervescent tablets in total.
- Marketing authorisation holder: Bayer d.o.o. Beograd, Omladinskih brigada 88b, Belgrade.
- Manufacturer: Bayer Bitterfeld GmbH, Bitterfeld-Wolfen, Germany.
Storage
- Store below 25 °C.
- Shelf life: 3 years; do not use after the expiry date on the pack.
- Keep out of the sight and reach of children.
- Return unused medicine to a pharmacy that collects unused medicines.
Frequently asked questions
Can children take Aspirin plus C?
No. The medicine must not be given to children and adolescents under 16, especially during viral infections such as flu or chickenpox, because of the risk of the rare but serious Reye's syndrome.
How many Aspirin plus C tablets can I take per day?
People aged 16 and over take 1–2 tablets, 4 to 8 hours apart, no more than 3 times and no more than 6 tablets a day. People over 65 take 1 tablet at a time, no more than 5 tablets a day.
How long can I take Aspirin plus C without a doctor?
Without medical advice, no more than 3 days for fever and no more than 3–4 days for pain. If symptoms last longer or get worse, see a doctor.
Can Aspirin plus C be taken with blood thinners?
Not without a doctor. Use together with oral anticoagulants is contraindicated, and with other medicines affecting blood clotting a doctor's or pharmacist's advice is needed because of the risk of bleeding.
Related information
For additional care and support with colds and flu, see also the Colds and flu category – products in this category do not replace the medicine you have been prescribed.
Sources
- ALIMS – Patient leaflet Aspirin® plus C, 400 mg/240 mg, effervescent tablets (licence 515-01-04294-21-001, revised December 2022)
- ALIMS – Summary of product characteristics Aspirin® plus C, 400 mg/240 mg, effervescent tablets (licence renewed 15.12.2022)
Sources checked on: 23 October 2026.
Pharmacy Online has a contract with the Daily Express courier service and it is delivered on the territory of the Republic of Serbia through this service. Exports of goods to foreign countries are done through DHL and PostExport.
For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.
Deliveries are not made on Saturdays and Sundays.
Additional information
The items will be packed so that they cannot be damaged by normal handling of the goods in transit. When picking up the product, the buyer is obliged to check for any damage and immediately advertise it to the courier who delivered the goods, or refuse to take over the shipment, which shows the external damage. Any subsequent product claims for shipping damage will not be considered.
When picking up the product, the customer is required to sign the delivery note taken by the Daily Express delivery worker. The delivery note is considered to be a receipt and delivery note.
The courier service delivers the goods to the address, ie. does not bring into the living space.
Delivery restrictions on goods
Delivery of items purchased on the site www.apotekaonline.rs is made exclusively through the Daily Express courier service in the territory of the Republic of Serbia. Delivery outside the territory of the Republic of Serbia, ie export of goods, is done exclusively through the service of DHL and PostExport Post of Serbia.
Shipping cost
For the territory of the Republic of Serbia:
For goods ordered up to 5.000,00 RSD, delivery charge is 350.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.
For international delivery:
For the export of goods abroad through the PostExport service of Post of Serbia, the shipping price is for:
- Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
- Zone II (Other European countries) - 1,790.00 RSD
- Zone III (Asia, Africa, America, Australia and other countries) - 2,650.00 RSD
Delivery time is 15 days or more (depending on the country of delivery)
For export of goods abroad through DHL service, the shipping price is 2,700.00 RSD. Delivery time is 1-5 business days (depending on the country of delivery)
Shipping cost is with tax. The price includes the delivery of the parcel to the buyer's address with the associated tax and customs at the seller's expense. A possible additional cost may be a customs charge against the buyer, depending on the country to which the package is being shipped.
For any additional questions, complaints or checking the current location of your shipment, please contact us at the following e-mail address: info@apotekaonline.rs
