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Water for injections
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- Stock: Zabrana online prodaje
- Brand: OSTALO
- Model: BR-60533166320303
Water for injections is sterile, pyrogen-free water used as a solvent – for dissolving, diluting and preparing medicines intended for parenteral use (injections and infusions). It is not itself a medicine given to the patient, but serves to prepare another medicine.
In Serbia, 5 mL ampoules (Galenika a.d. Belgrade) and 100, 250 and 500 mL bottles (B. Braun Adria RSRB d.o.o. Belgrade) are authorised. All forms are used only in healthcare institutions. Which volume to use and how is determined by the leaflet of the medicine being dissolved and by the doctor.
Important warning
- Water for injections is markedly hypotonic and must not be given on its own, especially not intravenously – it can cause haemolysis (breakdown of red blood cells) and resulting kidney damage.
- It may be given into a vein only after isotonicity has been achieved by adding a suitable substance.
- Solutions should be prepared under sterile conditions immediately before use; bottles and ampoules are for single use only.
Water for injections – authorised forms in Serbia
Key facts
| Composition | water for injections, no excipients |
|---|---|
| Pharmaceutical form | solvent for parenteral use |
| Appearance | clear, colourless liquid |
| Authorised volumes | 5 mL (ampoules); 100 mL, 250 mL and 500 mL (bottles) |
| Supply | for use in healthcare institutions only (Z) |
| Marketing authorisation holders | Galenika a.d. Belgrade; B. Braun Adria RSRB d.o.o. Belgrade |
Authorised medicines in Serbia
According to the medicines register (mediately.co/rs) and the ALIMS summaries of product characteristics, the following forms are authorised in Serbia:
| Medicine | Strength and form | Pack | Marketing authorisation holder | Supply |
|---|---|---|---|---|
| Water for injections (Voda za injekcije) | 5 mL, solvent for parenteral use (ampoule) | 50 ampoules (5 trays of 10) | Galenika a.d. Belgrade | healthcare institution (Z) |
| Water for injections B. Braun | 100 mL, solvent (LDPE Ecoflac plus bottle) | 20 bottles of 100 mL | B. Braun Adria RSRB d.o.o. Belgrade | healthcare institution (Z) |
| Water for injections B. Braun | 250 mL, solvent (LDPE Ecoflac plus bottle) | 10 bottles of 250 mL | B. Braun Adria RSRB d.o.o. Belgrade | healthcare institution (Z) |
| Water for injections B. Braun | 500 mL, solvent (LDPE Ecoflac plus bottle) | 10 bottles of 500 mL | B. Braun Adria RSRB d.o.o. Belgrade | healthcare institution (Z) |
What it is used for
Water for injections is used for dissolving, diluting and preparing suitable medicines intended for parenteral administration – for example powders for injection or concentrates that must be diluted before use.
How it is taken / used
- Dosing, rate and method of administration depend on the leaflet of the medicine being dissolved or diluted, as well as on the patient’s age, body weight, clinical condition and laboratory values.
- The same applies to children – dosing depends on the instructions for the dissolved medicine.
- Medicines should be dissolved or diluted immediately before use.
- When diluting hypertonic solutions, the dilution should be made so that the final solution is approximately isotonic.
When the medicine must not be used
- water for injections must not be used on its own
- the contraindications of the medicine being dissolved or diluted must be observed
Warnings and precautions
- Not for intravenous use on its own: because it lacks osmotically active substances, the solution is markedly hypotonic.
- Infusion of a large volume of a hypotonic solution prepared with water for injections can cause haemolysis of red blood cells and, as a result, haemoglobin-induced renal failure.
- When large volumes are given, electrolytes should be monitored regularly.
- Preparation is done under hygienic conditions as in hospitals and operating theatres, to keep it sterile.
- If water for injections is given intravenously on its own by mistake, water and electrolyte disturbances are corrected according to laboratory results; with extensive haemolysis, intensive care measures are needed.
Interactions with other medicines
No interactions of water for injections itself are known. Possible interactions between the substances and medicines to be dissolved or diluted should be considered.
Pregnancy and breastfeeding
The risks of use in pregnant and breastfeeding women are determined by the type of medicine being dissolved or diluted. Water for injections has no influence on the ability to drive.
Possible side effects
According to the SmPC (section 4.8), no side effects are known if water for injections is used as instructed.
Intravenous use of water for injections alone, without added substances, can cause haemolysis. The likelihood of other adverse reactions depends on the medicine added.
When to seek medical help immediately
- sudden weakness, shivering, back pain or dark red/brown urine during or after an infusion (possible signs of haemolysis)
- difficulty breathing, rash or swelling during administration of the dissolved medicine
- pain, redness or swelling at the infusion site
Pharmacist's Advice
Water for injections is an aid for preparing medicines and is never given into a vein on its own. In a healthcare institution, only a clear, colourless liquid from an undamaged ampoule or bottle is used, immediately after opening, and any remainder is discarded.
If you dissolve a medicine on your doctor’s instructions (e.g. a powder for injection you receive as therapy), use exactly the volume of solvent stated in the leaflet for that medicine and work sterilely. If in any doubt, ask a pharmacist or nurse.
Availability and price
Water for injections is a medicine for use in healthcare institutions and is not available for online purchase at ApotekaOnline, which is why no price is shown. For further information, contact our pharmacists.
Storage
5 mL ampoules (Galenika): store below 25 °C in the original package in order to protect from light; shelf life 5 years. B. Braun bottles: the medicine does not require any special storage conditions; shelf life of the unopened product 3 years. After adding a medicine, the solution should be used immediately; if that is not possible, for no longer than 24 hours at 2–8 °C, unless prepared under controlled aseptic conditions.
Frequently asked questions
Can water for injections be drunk or used for rinsing?
No. It is a solvent for preparing medicines for parenteral use and is used only in healthcare institutions.
Why must water for injections not be given into a vein on its own?
Because it is markedly hypotonic and can cause haemolysis of red blood cells.
Which volumes are available in Serbia?
5 mL ampoules and 100, 250 and 500 mL bottles.
How long can an opened bottle be kept?
It is not kept – the liquid should be used immediately after opening and the remainder discarded.
Sources
- ALIMS – Summary of product characteristics for Water for injections 5 mL (Galenika)
- ALIMS – Summary of product characteristics for Water for injections B. Braun (100, 250 and 500 mL)
- Mediately – Serbian medicines register
Date sources and register were checked: 6 November 2026.
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For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.
Deliveries are not made on Saturdays and Sundays.
Additional information
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Shipping cost
For the territory of the Republic of Serbia:
For goods ordered up to 5.000,00 RSD, delivery charge is 350.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.
For international delivery:
For the export of goods abroad through the PostExport service of Post of Serbia, the shipping price is for:
- Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
- Zone II (Other European countries) - 1,790.00 RSD
- Zone III (Asia, Africa, America, Australia and other countries) - 2,650.00 RSD
Delivery time is 15 days or more (depending on the country of delivery)
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