-150x150w.webp)
-150x150w.webp)
Sinedol gel (500 IU/g + 150 mg/g + 25 mg/g) – bruises, sprains and swelling
Pogledajte blok ispod gde možete pronaći proizvode koji su slični ili imaju slična dejstva kao proizvod na čijoj se stranici nalazite.
- Stock: Zabrana online prodaje
- Brand: HEMOFARM-EN
- Model: BR-05263210
Sinedol gel is a medicine for use on the skin containing three active substances: heparin sodium (500 IU/g), dimethyl sulfoxide (150 mg/g) and dexpanthenol (25 mg/g). It belongs to the group of vasoprotectives – heparins or heparinoids for topical use (ATC C05BA53).
Heparin prevents blood clotting and helps bruises fade, dimethyl sulfoxide reduces inflammation and pain and enhances the penetration of other substances through the skin, and dexpanthenol protects and cares for the skin. The medicine is intended for adults and comes in a 40 g aluminium tube.
Important warning
- Supply status in Serbia: medicine available without a prescription (according to the leaflet approved by ALIMS).
- It must not be used in children and adolescents or in severe liver and/or kidney impairment.
- Do not apply to open wounds, damaged skin or mucous membranes; in vein disorders do not massage the affected area.
- If there is no improvement after 1 to 2 weeks or symptoms get worse, consult a doctor.
- This page is for information only and is not an offer to buy the medicine online.
What is Sinedol gel used for and how is it applied correctly?
Key facts about the medicine
| Medicine name | Sinedol®, (500 IU/g + 150 mg/g + 25 mg/g), gel |
|---|---|
| Active substances | heparin sodium, dimethyl sulfoxide, dexpanthenol |
| Strength | 1 g of gel contains 500 IU heparin sodium, 150 mg dimethyl sulfoxide and 25 mg dexpanthenol |
| Pharmaceutical form | gel for cutaneous use |
| Therapeutic group | vasoprotectives; heparins or heparinoids for topical use (ATC C05BA53) |
| Pack | aluminium tube containing 40 g of gel, carton (1 × 40 g) |
| Marketing authorisation holder and manufacturer | Hemofarm AD Vršac, Republic of Serbia |
| Supply status | available without a prescription |
What is Sinedol gel used for?
According to the patient leaflet, Sinedol gel is intended for adults for:
- swelling, haematomas (bruises) and inflammation caused by blunt injuries of muscles, tendons, synovia, ligaments and joints – bruises, contusions, strains and sprains
- tennis elbow, inflammation of tendons and synovia, and bursitis
- acute neuralgic pain, inflammation and limited mobility in the shoulder area
- acute complaints in leg vein disorders: pain, swelling and superficial inflammation
How is it used and dosed?
The medicine is for use on the skin only (cutaneous use). In adults the gel is applied 1–2 times a day to the affected area in a thin layer, without rubbing it in.
- The skin must be dry and clean before application.
- Do not apply the gel to open wounds, damaged skin or mucous membranes.
- If a bandage is used, do not cover the skin with an occlusive (airtight) dressing; apply a breathable bandage only after the gel has been absorbed.
- On a doctor's recommendation, the gel can also be used for iontophoresis (applied under the cathode).
- Duration: if you do not feel better or feel worse after 1 to 2 weeks, consult a doctor.
Special patient groups
- Children and adolescents: the medicine must not be used; its safety has not been established.
- People with severe liver and/or kidney impairment: the medicine must not be used.
- Elderly: the leaflet does not specify a dose adjustment; general precautions apply.
Contraindications – when the medicine must not be used
Sinedol must not be used:
- in case of hypersensitivity to heparin, dimethyl sulfoxide, dexpanthenol or any of the excipients
- in children and adolescents
- in severe impairment or reduced function of the liver and/or kidneys
Precautions and warnings
Use is not recommended if:
- you have asthma
- you are pregnant or breastfeeding
- you have a circulatory disorder
- you have systemic lupus erythematosus
- the skin or mucous membrane at the application site is already damaged
No other medicine may be applied to the same skin area immediately before or after applying Sinedol gel. In vein disorders, the affected area must not be massaged because of possible thromboembolism. The medicine contains macrogolglycerol hydroxystearate (hydrogenated castor oil), which may cause skin reactions.
Interactions with other medicines, alcohol and food
Sinedol gel should not be used at the same time as non-steroidal anti-inflammatory medicines containing sulindac. Tell your doctor or pharmacist about all medicines you use. Interactions with food and alcohol are not described in the leaflet.
Pregnancy and breastfeeding
Sinedol should not be used during pregnancy. Because at least one substance of the medicine passes into breast milk, it should not be used during breastfeeding either.
Driving and using machines
The effect on the ability to drive and use machines has not been specifically studied, but according to the leaflet a negative effect is unlikely.
Possible side effects
- Occasionally: skin redness, itching or stinging (due to dilation of blood vessels caused by dimethyl sulfoxide); these reactions usually disappear as treatment continues.
- In some cases: allergic skin reactions.
- A garlic-like breath odour may occasionally occur (due to the metabolite dimethyl sulfide); the change in taste disappears after a few minutes.
- Nausea, vomiting, diarrhoea, constipation and loss of appetite have also been described.
- In isolated cases: hives and angioneurotic oedema (swelling of the skin and mucous membranes of the face and neck) – contact a doctor.
Suspected side effects can be reported to your doctor, pharmacist or the Medicines and Medical Devices Agency of Serbia (ALIMS).
Overdose, missed dose and stopping treatment
- Overdose: if you have applied more than prescribed, contact a doctor. According to the SmPC, no cases of overdose have been reported and toxic effects are not expected because of topical use.
- Missed dose: apply the gel as soon as possible; if it is almost time for the next application, skip the missed one. Do not apply a double dose.
- Stopping treatment: stopping suddenly does not cause any changes.
When to seek medical help immediately?
- swelling of the face, lips, tongue or neck, hives or difficulty breathing (signs of an allergic reaction)
- sudden severe pain, redness and swelling of the whole leg, especially with shortness of breath or chest pain
- severe pain, deformity or inability to bear weight on the injured joint after an injury
- no improvement or worsening of symptoms after 1 to 2 weeks of use
Pharmacist's advice
Apply Sinedol in a thin layer to clean, dry skin and let it absorb – do not rub it in and do not massage the affected area if the complaint is vein-related. Do not apply other creams or gels to the same area.
A temporary garlic smell or taste after application is an expected effect of dimethyl sulfoxide and is no cause for concern. The medicine is not intended for children, pregnant or breastfeeding women.
Availability and price
The medicine is available without a prescription, but under the regulations of the Republic of Serbia it cannot be ordered online. This page is for information only.
Please contact a pharmacy to check availability.
Related information
For further questions about using this medicine and choosing supporting products, please ask a pharmacist.
For additional care and support with sprains, bruises and swelling, see also the Ligaments and sprains category – products in this category do not replace the medicine you have been prescribed.
Composition, packaging and manufacturer
- 1 g of gel contains: heparin sodium 500 IU, dimethyl sulfoxide 150 mg, dexpanthenol 25 mg.
- Excipients: isopropyl alcohol; carbomer 940; macrogolglycerol hydroxystearate; trolamine; dwarf pine essential oil; rosemary essential oil; lemon essential oil; purified water.
- Appearance: colourless, clear, homogeneous gel with a characteristic odour.
- Pack: aluminium tube with plastic cap containing 40 g of gel, in a carton with the leaflet.
- Marketing authorisation holder and manufacturer: Hemofarm AD Vršac, Beogradski put bb, Vršac, Republic of Serbia.
Storage
- Store below 25 °C.
- Shelf life of the unopened medicine is 5 years; after first opening 4 years when stored below 25 °C.
- Keep out of the sight and reach of children; do not use after the expiry date on the pack.
- Do not dispose of unused medicine via wastewater or household waste; return it to a pharmacy that collects unused medicines.
Frequently asked questions
Why do I smell garlic after applying Sinedol gel?
Dimethyl sulfoxide is partly converted in the body to dimethyl sulfide, which causes a garlic-like breath odour. The leaflet states that this occurs occasionally and that the change in taste disappears after a few minutes.
Can I use Sinedol gel on a child after a bump?
No. According to the leaflet, the medicine must not be used in children and adolescents. For injuries in children, ask a doctor or pharmacist.
Can I put a bandage over Sinedol gel?
Yes, but not an occlusive (airtight) one. Apply a breathable bandage only after the thin layer of gel has been absorbed.
Can Sinedol be applied to varicose veins?
The medicine is used for acute pain, swelling and superficial inflammation in leg vein disorders, but the affected area must not be massaged because of possible thromboembolism. If the whole leg suddenly swells and hurts, see a doctor immediately.
Sources
- ALIMS – Patient leaflet Sinedol, (500 IU/g + 150 mg/g + 25 mg/g), gel (December 2024)
- ALIMS – Summary of Product Characteristics Sinedol, gel (authorisation 001079454 2024 of 17.12.2024)
Date sources were checked: 23 October 2026.
Pharmacy Online has a contract with the Daily Express courier service and it is delivered on the territory of the Republic of Serbia through this service. Exports of goods to foreign countries are done through DHL and PostExport.
For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.
Deliveries are not made on Saturdays and Sundays.
Additional information
The items will be packed so that they cannot be damaged by normal handling of the goods in transit. When picking up the product, the buyer is obliged to check for any damage and immediately advertise it to the courier who delivered the goods, or refuse to take over the shipment, which shows the external damage. Any subsequent product claims for shipping damage will not be considered.
When picking up the product, the customer is required to sign the delivery note taken by the Daily Express delivery worker. The delivery note is considered to be a receipt and delivery note.
The courier service delivers the goods to the address, ie. does not bring into the living space.
Delivery restrictions on goods
Delivery of items purchased on the site www.apotekaonline.rs is made exclusively through the Daily Express courier service in the territory of the Republic of Serbia. Delivery outside the territory of the Republic of Serbia, ie export of goods, is done exclusively through the service of DHL and PostExport Post of Serbia.
Shipping cost
For the territory of the Republic of Serbia:
For goods ordered up to 5.000,00 RSD, delivery charge is 350.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.
For international delivery:
For the export of goods abroad through the PostExport service of Post of Serbia, the shipping price is for:
- Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
- Zone II (Other European countries) - 1,790.00 RSD
- Zone III (Asia, Africa, America, Australia and other countries) - 2,650.00 RSD
Delivery time is 15 days or more (depending on the country of delivery)
For export of goods abroad through DHL service, the shipping price is 2,700.00 RSD. Delivery time is 1-5 business days (depending on the country of delivery)
Shipping cost is with tax. The price includes the delivery of the parcel to the buyer's address with the associated tax and customs at the seller's expense. A possible additional cost may be a customs charge against the buyer, depending on the country to which the package is being shipped.
For any additional questions, complaints or checking the current location of your shipment, please contact us at the following e-mail address: info@apotekaonline.rs
