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Milgamma 100 mg/100 mg coated tablets, 30 and 60 tablets – uses, instructions and important information

Milgamma 100 Tablets
Milgamma 100 mg/100 mg coated tablets, 30 and 60 tablets – uses, instructions and important information
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Milgamma 100, 100 mg/100 mg, coated tablets is a medicine containing benfotiamine and pyridoxine hydrochloride, active substances related to vitam..
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  • Stock: Zabrana online prodaje
  • Brand: WORWAG PHARMA
  • Model: BR-88881

Milgamma 100, 100 mg/100 mg, coated tablets is a medicine containing benfotiamine and pyridoxine hydrochloride, active substances related to vitamins B1 and B6. Each coated tablet contains 100 mg of benfotiamine and 100 mg of pyridoxine hydrochloride.

The medicine is intended for the treatment of systemic neurological disorders caused by a confirmed deficiency of vitamins B1 and B6. Milgamma 100 is available in packs of 30 and 60 coated tablets. The composition and strength of the tablets are the same in both pack sizes; only the number of tablets in the box differs.

Important: The information on this page does not replace advice from a doctor or pharmacist. Use this medicine only as recommended by a healthcare professional and in accordance with the official package leaflet.

What does Milgamma 100 contain?

  • Active substances: benfotiamine and pyridoxine hydrochloride.
  • Strength: 100 mg of benfotiamine and 100 mg of pyridoxine hydrochloride per tablet.
  • Pharmaceutical form: coated tablet.
  • Pack sizes: 30 or 60 coated tablets.
  • Route of administration: oral use.
  • Dispensing status: this medicine is available on prescription only.

Each tablet contains sucrose. If your doctor has told you that you are intolerant to certain sugars, speak to your doctor before taking this medicine.

What is Milgamma 100 used for?

Milgamma 100 is used for the treatment of systemic neurological disorders caused by a confirmed deficiency of vitamins B1 and B6.

This medicine is not intended for self-treatment of every type of pain, tingling, burning, numbness or other neurological symptoms. The cause of the symptoms and the need for treatment should be assessed by a doctor.

How is Milgamma 100 taken?

Always take this medicine exactly as your doctor has told you. Check with your doctor or pharmacist if you are not sure.

According to the official package leaflet, unless otherwise prescribed by the doctor, the recommended dose for adults is one coated tablet daily. In acute cases, after assessing the patient, the doctor may increase the dose to one coated tablet three times daily.

The tablet should be swallowed with a sufficient amount of liquid. Patients should not increase the dose or extend the duration of treatment on their own.

Treatment review: After no more than four weeks, the doctor should assess whether the increased dose is still necessary. Whenever possible, the dose should be reduced to one tablet daily in order to reduce the risk of neuropathy associated with prolonged use of vitamin B6.

The dose and duration of treatment may depend on the patient’s medical condition, age, confirmed vitamin deficiency, other medicines being used and the doctor’s assessment.

Use in children and adolescents

There are insufficient data on the use of Milgamma 100 in children and adolescents under 18 years of age. Therefore, the medicine is not used in this age group.

When must Milgamma 100 not be used?

The medicine must not be used by people who are allergic to benfotiamine, thiamine, pyridoxine hydrochloride or any of the other ingredients of the medicine.

Because it contains sucrose, the medicine should not be used by patients with certain rare inherited disorders affecting the tolerance or absorption of sugars, unless otherwise assessed by a doctor.

Warnings and precautions

Before starting treatment, tell your doctor or pharmacist about any medical conditions you have and all medicines, vitamins or supplements you use.

Long-term use of vitamin B6 in high doses, particularly for periods longer than six months, may cause peripheral sensory neuropathy, which is damage to the peripheral nerves.

Contact your doctor: If tingling, burning, numbness, altered sensation in the hands or feet, or other unusual neurological symptoms occur or worsen during treatment, do not increase the dose or extend the treatment on your own.

Interactions with other medicines

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

It is particularly important to mention if you are using:

  • Levodopa, because vitamin B6 may affect its action;
  • hydralazine, isoniazid, D-penicillamine or cycloserine;
  • 5-fluorouracil, because it may affect thiamine;
  • oral contraceptives containing oestrogen;
  • other medicines, vitamins or supplements containing vitamin B6.

Long-term alcohol consumption may also be associated with vitamin B6 deficiency. Do not change or stop any other treatment without consulting your doctor.

Pregnancy and breastfeeding

If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.

Because of the high doses of the active substances, Milgamma 100 may be used during pregnancy and breastfeeding only in cases of a confirmed deficiency of vitamins B1 and B6 and when the doctor considers treatment necessary.

Vitamins B1 and B6 pass into breast milk. High doses of vitamin B6 may reduce milk production. The decision to use this medicine during pregnancy or breastfeeding must be made by a doctor after assessing the expected benefits and possible risks.

Driving and using machines

According to the official package leaflet, Milgamma 100 has no or negligible influence on the ability to drive and use machines.

Possible side effects

Like all medicines, Milgamma 100 can cause side effects, although not everybody gets them.

Very rare side effects, which may affect up to 1 in 10,000 people, include:

  • hypersensitivity reactions;
  • rash or hives;
  • a serious allergic reaction or shock;
  • nausea and other gastrointestinal problems.

Side effects with an unknown frequency:

  • peripheral sensory neuropathy, particularly with prolonged use of high doses of vitamin B6.

Seek urgent medical help: If you experience difficulty breathing, swelling of the face, lips, tongue or throat, severe weakness, a sudden drop in blood pressure or other signs of a serious allergic reaction, stop taking the medicine and seek immediate medical assistance.

Tell your doctor or pharmacist about any side effects, including any possible side effects not listed in the official package leaflet.

What should you do if you take more than you should?

Very high doses of vitamin B6 may cause neurotoxic effects. Extremely high doses may lead to seizures and other serious symptoms.

If you have taken more medicine than prescribed or experience unexpected symptoms, contact your doctor or the nearest healthcare facility immediately.

What should you do if you forget a dose?

Do not take a double dose to make up for a forgotten tablet. Continue treatment as instructed by your doctor or consult a pharmacist.

Stopping treatment

Do not stop prescribed treatment on your own. Any dose adjustment or discontinuation should be made after consulting your doctor.

How should the medicine be stored?

  • Keep this medicine out of the sight and reach of children.
  • Store below 25 °C.
  • Store in the original package in order to protect it from light.
  • Do not use the medicine after the expiry date stated on the package.

Do not dispose of unused medicines via wastewater or household waste. Return them to a pharmacy that collects unused medicines from the public.

Availability and price of the medicine

Milgamma 100 is available on prescription only.

This medicine cannot be purchased online. The information on this page is provided for educational purposes. For information about availability, price and dispensing status, contact a pharmacy, doctor or pharmacist.

The medicine is available in packs of 30 and 60 coated tablets. Availability of a specific pack size may vary between pharmacies.

Pharmacist’s advice

Pharmacist’s advice: Milgamma 100 contains a high dose of vitamin B6. Do not combine it with other products containing vitamin B6 without first checking the total daily amount, as prolonged use of high doses may increase the risk of peripheral nerve damage.

Before starting treatment, check whether this medicine is suitable for your medical condition and compatible with other medicines you use. Do not change the dose or stop prescribed treatment without consulting a doctor or pharmacist.

Ljubica Barbulović, Master of Pharmacy

Related information

Read more about the causes, symptoms and medical assessment of peripheral nerve damage in the following guide:

What is neuropathy, what are the symptoms and how is it treated?

In the vitamins and minerals category, you can view products that are available for purchase through the website.

Note: Food supplements are not a substitute for Milgamma 100 or for treatment prescribed by a doctor. Because they may contain vitamin B6, check the composition of any product and consult a doctor or pharmacist before combining it with this medicine.

Frequently asked questions about Milgamma 100

What is Milgamma 100 used for?
It is used for the treatment of systemic neurological disorders caused by a confirmed deficiency of vitamins B1 and B6.

Which active substances does it contain?
Each tablet contains 100 mg of benfotiamine and 100 mg of pyridoxine hydrochloride.

Is Milgamma 100 available on prescription?
Yes. This medicine is available on prescription only.

Are packs of 30 and 60 tablets available?
Yes. The medicine is available in packs of 30 and 60 coated tablets. The composition and strength of each tablet are the same in both packs.

What should I do if I forget a dose?
Do not take a double dose. Continue treatment as instructed by your doctor or consult a pharmacist.

Can the medicine be used during pregnancy or breastfeeding?
Only when a doctor confirms a deficiency of vitamins B1 and B6 and considers treatment necessary.

Can Milgamma 100 be purchased online?
No. The medicine is available on prescription and cannot be purchased online through this website.

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