Megoxi 40 mg/mL oral suspension – megestrol acetate for loss of appetite and weight
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- Stock: Zabrana online prodaje
- Brand: PHARMA SWISS
- Model: BR-68891206526
Megoxi is an oral suspension containing megestrol acetate 40 mg/mL – a progestogen related to the natural hormone progesterone.
The medicine helps to correct the loss of appetite and body weight that often occurs in patients with cancer or AIDS.
Important warning
- Dispensing status: the medicine is available on prescription only.
- It must not be taken with previous blood clotting problems (thromboembolic disorders); caution in thrombophlebitis.
- It may raise blood sugar in people with diabetes.
- It is not recommended in pregnancy; effective contraception should be used during treatment and breastfeeding stopped.
- This page is for information only and is not an offer to buy the medicine online.
What is Megoxi oral suspension used for and how is it taken?
Basic information about the medicine
| Medicine name | Megoxi®, 40 mg/mL, oral suspension |
|---|---|
| Active substance | megestrol acetate |
| Strength | 40 mg/mL |
| Pharmaceutical form | oral suspension |
| Therapeutic group | endocrine therapy – progestogens (ATC L02AB01) |
| Pack | HDPE bottle with 240 mL and measuring cup marked 10, 20 and 30 mL |
| Marketing authorisation holder / manufacturer | PharmaSwiss d.o.o. Belgrade (marketing authorisation holder and manufacturer) |
| Dispensing status | R – prescription only |
What is Megoxi used for?
According to the SmPC, Megoxi is used:
- to treat anorexia and weight loss due to malignant neoplasm or AIDS, in patients of both sexes.
How is Megoxi used and dosed?
The dose is decided by the doctor based on your condition. According to the leaflet:
- The recommended dose is 400–800 mg (10–20 mL) daily as a single dose.
- Measure the dose with the cup provided (marked 10, 20 and 30 mL).
- In people aged 65 and over the doctor may start with the lowest dose and monitor kidney function.
- To assess efficacy, the medicine should be taken for at least 2 months without interruption; continue until your doctor tells you otherwise.
Special patient groups
- Children: use is not recommended.
- Over 65 years: the doctor may monitor kidney function from time to time.
Contraindications – when the medicine must not be used
- allergy to megestrol acetate or any of the excipients;
- previous blood clotting problems (thromboembolic disorders).
Precautions and warnings
- thrombophlebitis (swollen veins with clots) now or in the past;
- diabetes – blood sugar may rise; if you notice raised values, contact your doctor;
- the medicine contains sucrose (caution in sugar intolerance) and sodium benzoate (40 mg per 20 mL); less than 1 mmol sodium per 20 mL.
Interactions with other medicines, food and drink
- There are currently no data on the effect of Megoxi on other medicines when used together. Tell your doctor about all medicines you take.
Pregnancy and breastfeeding
- Not recommended in pregnancy; women of childbearing age should avoid pregnancy and use effective contraception.
- Breastfeeding should be stopped during treatment because of possible side effects in the infant.
Driving and using machines
- The medicine has no or negligible influence on the ability to drive and use machines.
Possible side effects
- Very common (more than 1 in 10): increased appetite and weight gain (not related to fluid retention), shortness of breath, hot flushes and flushing of face and neck, high blood pressure, raised blood sugar, rounded face ("moon face"), constipation, swollen veins due to blood clots, blood clots in the lungs.
- Common (up to 1 in 10): temporary worsening of the underlying disease, mood changes, numbness or tingling in the fingers, heart attack or heart failure, hair loss, diarrhoea, tiredness, weakness, impotence, flatulence, frequent urination, nausea and vomiting, breakthrough or spotting vaginal bleeding, swelling (mainly of joints/ankles), pain, rash and hives.
Overdose, missed dose and stopping treatment
- Overdose: go to the nearest hospital or contact a doctor immediately and take the medicine pack with you.
- Missed dose: if you remember within a few hours, take it; if it is nearly time for the next dose, skip the missed one. Do not take a double dose.
- Stopping treatment: continue the medicine until your doctor tells you otherwise.
When to seek medical help immediately?
- swelling of the face, lips or tongue, rash, difficulty breathing (allergic reaction) – stop the medicine;
- signs of a blood clot: pain, swelling or numbness of a leg (especially the calf), sudden shortness of breath, chest pain;
- loss of coordination, slurred speech, sudden weakness, severe headache or fainting;
- severe thirst, frequent urination and marked tiredness (possible high blood sugar).
Pharmacist's advice
Shake the bottle before each use and always measure the dose with the cup provided – a kitchen spoon is not accurate. After first opening the suspension can be used for 48 days, so write the opening date on the carton.
During prolonged immobility move your legs often and drink enough fluids; report calf pain or swelling, and sudden shortness of breath, to your doctor immediately.
Availability and price
Megoxi is a prescription-only medicine. ApotekaOnline.rs does not sell prescription medicines online, and this page is for information only.
Please check availability and price at a pharmacy with a valid prescription.
Related information
Megestrol acetate is used as part of specialist treatment in cancer or AIDS. For questions about nutrition during treatment, please contact the doctor managing your treatment.
Composition, pack and manufacturer
- Active substance: megestrol acetate 40 mg in 1 mL of oral suspension.
- Excipients: macrogol 1500; polysorbate 80; anhydrous citric acid; sodium citrate; sodium benzoate; sucrose; xanthan gum; orange flavour (orange oil, ethanol, water); purified water.
- Appearance: homogeneous white suspension with an orange odour.
- Pack: white HDPE bottle with 240 mL oral suspension and a plastic measuring cup marked 10, 20 and 30 mL, in a carton.
- Marketing authorisation holder and manufacturer: PharmaSwiss d.o.o. Belgrade, Batajnički drum 5A, Belgrade.
- Marketing authorisation number: 515-01-03506-20-002 of 11 October 2021 (renewal).
Storage
- Store below 25 °C.
- Shelf life after first opening: 48 days when stored below 25 °C.
- Keep out of the sight and reach of children.
Frequently asked questions
How much Megoxi suspension is taken daily?
According to the leaflet, the recommended dose is 400–800 mg, i.e. 10–20 mL daily, as a single dose. The exact dose is decided by the doctor.
When can an effect be seen?
To assess efficacy, the medicine should be taken for at least 2 months without interruption.
Is Megoxi the same as Megace suspension?
Both contain megestrol acetate 40 mg/mL and have the same indication, but they differ in excipients (e.g. orange flavour in Megoxi), measuring cup and shelf life after opening. Do not switch without advice from your doctor or pharmacist.
Which symptoms should I watch for?
Signs of a blood clot (leg pain and swelling, shortness of breath, chest pain), signs of allergy and raised blood sugar – in these cases contact your doctor immediately.
Sources
- ALIMS – Patient information leaflet Megoxi (PIL)
- ALIMS – Summary of product characteristics Megoxi (SmPC)
Sources checked on: 25 October 2026.
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