RUPURUT

Sales of this drug over the Internet is prohibited by the law of the Republic of Serbia, while advertising the same way the Internet allowed solely as a reminder and has the purpose of information.

Rulebook on ADVERTISING the DRUG, or MEDICAL FUNDS Etc. Gl. RS, 79/2010 CAN BE SEEN HERE.

INSTRUCTIONS FOR PATIENTS

Carefully read these instructions because it sadrii information that is relevant to You.
This medicine you can buy without a medical prescription, to treat minor ailments without the help of your doctor. In addition, it is necessary to carefully use this medicine to get the best results from it.
The manual save. You may want to read it again.
If you need any more additional information or advice, please contact your physician or to the pharmacist.
If your symptoms get worse or if it does not get better after 7 days, be sure to visit Your doctor.

Protected name of drug, strength, pharmaceutical form: RUPURUT ®, 500 mg chewable tablets
Unprotected, generic name: hidrotalcit

The contents of the active substances: Every Rupurut ® tablets for chewing gum contains 500 mg of hidrotalcita.
The contents of secondary substances: Auxiliary substances are: mannitol, corn starch, magnesium stearate, sodium saccharin, banana-flavor, the aroma of peppermint.

The name and address of the authorisation for placing in service for a cure: Bayer driver, Omladinskih brigada avalska St., 11070 Beograd
The name and address of manufacturer: Bayer Bitterfeld GmbH, Greppin OT, Salegaster Chaussee 1, Bitterfeld-Wolfen, Germany

1. What is CURE RUPURUT ® and what he's supposed to do.

COMPOSITION:
One Rupurut ® tablets for chewing gum contains 500 mg hidrotalcita, corresponding to the capacity for neutralization of minimum 13 mEq hlorovodonične acid.

Pharmaceutical form and contents: chewable tablets, 500 mg hidrotaicit

Package:
Chewable tablets Rupurut ® is available in a box of 20 tablets.

20 tablets for chewing-number solution and date: 484/2007/12 of 07.02.2007.

HOW TO CURE RUPURUT ® WORK?
Rupurut ® is a drug that reduces the acidity of the gastric juice neutrališući hlorovodoničnu acid. He is a modern day antacid that contains hidrotalcit.

WHEN THE CURE RUPURUT ® USED?
Rupurut ® chewable tablets are used for relief of symptoms with disorders that require reducing stomach acidity:
-gastric ulcer and dvanaestopalačnom hose
-Mustard and želudačnih disorders caused by acid

2. What YOU NEED to READ BEFORE USING the DRUG.
Alert the doctor if you are taking your pills, you have some other, chronic disease, a disorder of metabolism, preosetijivi you are on medication or have had an allergic reaction to some of the rijih.

WHEN YOU CAN'T TAKE THE CURE:
Chewable tablets Rupurut ® must not be used:
-If you are hypersensitive to hidrotalcit or to any other component of the drug.
-Patients with disorder of work (creatinine clearance 30 mL/min <) can use Rupurut ® tablets for chewing only on the condition that the level of serum magnesium and aluminium regularly checks.
-Patients with low concentration of phosphate in the blood (hypophosphataemia) must not use Rupurut ® chewable tablets without prior consultation with a doctor.

WARNINGS AND PRECAUTIONS:

If you have persistent disorders želudačni and constantly present, this can be a sign of a serious condition, such as an ulcer in the stomach or ulcers on the colon dvanaestopalačnom. Treatment tablets for chewing Rupurut ® therefore shouldn't take longer than 14 days without a doctor's examination.

Please consult a doctor immediately if you get katranaste stools, blood in the stool or vomit.

Long-term use of tablets for chewing Rupurut ® requires regular validation of levels of aluminium in pacijenala. Aluminum level should not exceed 40 pg/l.

In patients with renal impairment, including patients on hemodialysis, and chronic use of larger doses can increase levels of magnesium and aluminum in the body.

For this reason, patients with impaired renal function should avoid long-term use and higher doses. Long-term use of high doses, disorder of nutrients in the gut and diet with low phosphate content (such as malnutrition or undernourishment) can cause a decline in phosphate with risk of disorders of bone composition due to inadequate installation minerals (osteomalacija).

Chewable tablets Rupurut ® should not be used in children under 14 years of age because there is not enough experience for this age group.

TAKING THE DRUG WITH FOOD OR DRINKS RUPURUT:
-Concomitant use of tablets for chewing Rupurut ® and acidic beverages (such as fruit juices, wine) lead to unwanted increases in aluminum absorption from the intestine.
-Effervescent tablets also contain fruit acids that may increase the absorption of aluminum.

APPLICATION OF UTRUDNOĆI AND BREASTFEEDING:

Before you start taking any other medications, consult your doctor or tarmaceutom.

During pregnancy and breastfeeding hidrotalcit should be used only for brief periods of time in order to avoid the emergence of increased amounts of aluminium in children.

Aluminum and magnesium components go into the fruit, but are also found in breast milk, so it does not exclude the possibility of a longer usage can lead to accumulation of aluminium and magnesium in the tissues of the fetus and newborn. Risks to the newborn is unlikely because only small quantities cannot be absorbed.

There are no published reports of harmful effects hidrotalcita during pregnancy or during lactation. However, no specific study on children of those mothers who used hidrotalcit during pregnancy or during lactation, which could turn off unwanted effects.

INFLUENCE ON PSYCHOPHYSICAL ABILITIES WHEN A MOTOR VEHICLE AND MACHINERY:
Rupurut ® has no influence on the psychophysical abilities when a motor vehicle and machinery.

WHAT YOU NEED TO BE AWARE IF YOU ARE TAKING OTHER MEDICATIONS?

Note that this information may apply to medicines that you no longer drink, as well as the medications that you plan to take in the future. Notify your doctor or tarmaceuta if you are taking, or have recently taken any other medication, including medicine being purchased without medical prescription.

Rupurut ® chewable tablets can affect the absorption, and consequently the efficiency of other substances. Speed of dikumarola is increasing. Significantly reduce absorption are described with specific antibiotics (such as tetracycline and derivatives from hinolonskih groups such as ciprofloxacin, ofloksacin and norfloksacin), substances that are used to improve cardiac (kardiotonični glycosides) , and ketoconazole, hlorokvina, chlorpromazine, rifampicin, izonijazida. Also, disturbed and absorption of indomethacin, salt, iron, vitamins, captopril, phenytoin, thyroid hormons, etc.

Also, care should be taken and the possible impact of Rupurut ® tablets for chewing on rastvorljivost medication that is excreted in urine, for example. salicilati or quinidine.

Therefore, other preparations should always take 2-3 hours before or after Rupurut ® tablets for chewing.

3. HOW to CURE RUPURUT ® UPOTREBUAVA?

If you think those Rupuruf too weak or strong works on Your system, contact your physician or to the pharmacist.

The drug must be taken in the manner as prescribed in the instructions (unless your doctor has prescribed otherwise). If you do not follow the instructions, the drug will not work properly.

Adults and children over 14 years:
One to two tablets (500 mg-1000 mg hidrotalcita), three to four times a day for one to two hours after eating, at bedtime or when the occurrence of želudačnih problems.

The daily dose must not exceed 12 tablets for chewing gum, which is equivalent to 6000 mg hidrotalcita.

Other products should always take 2-3 hours before or after Rupurut ® tablets for chewing.

The duration of treatment depends on the type, severity and the progress of the disorder.

If symptoms last longer than two weeks of treatment, should consult a doctor.

IF YOU TAKE MORE MEDICINE THAN IT SHOULD:
If you take a higher dose of Rupurut ® than it should, speak with Your doctor or pharmacist. Poisoning Rupurut ® tablets for chewing is unlikely due to a weak absorption of aluminium and magnesium. An overdose can cause changes in the characteristics of chairs such as soft stools or increase in frequency. Therapeutic measures in these cases generally are not required.

IF YOU FORGET TO TAKE THE MEDICINE RUPURUT:

Never take a double dose of supply that you skip to take iekl

WHAT HAPPENS IF YOU SUDDENLY STOP TAKING MEDICINE RUPURUT ®?
You always need to consult a doctor before you decide to stop treatment or stop taking Rupurut ® tablets for chewing, for example because of unwanted effects.

4. UNWANTED EFFECTS of MEDICATION:

Large doses can cause soft or frequent Chair. However, these signs are unlikely at the recommended doses. In patients with severe renal impairment, including patients on hemodialysis, the use of products containing magnesium and aluminium, such as Rupurut ® chewable tablets, can cause increase magnesium levels-and aluminium in blood . Patients with kidney disorders work taking large doses over a longer period of time may be subject to deponovanju of aluminum, especially in nervous tissue with poremeća-the work of the brain (encephalopathy and dementia), and on the bone with bone (razmekšavanjem osteomalacija) and sledstvenim by creating stones in the kidney. Accumulation of magnesium leads to toxicity with low pressure, slow-German heart rate with arrhythmia, mental depression and respiratory disorder.

For this reason, patients with the disorder in the work of the kidneys using Rupurut ® chewable tablets over a longer period of time, you need to check regularly the level of aluminum.

Due to drug reaction component in colon with phosphates from food, in the case of a fixed application of larger doses, decreased phosphate intake through food or their abnormal absorption in the intestines, you may experience a decrease in amount of phosphate in the body when there is a risk of composition of bone disorders (osteomalacija) and increased absorption of calcium.

If you notice any symptoms that might be adverse reactions to the medication, not Rupurut ® by