ASPIRIN 500 mg tablets – pain and fever
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- Stock: Zabrana online prodaje
- Brand: BAYER SCHERING PHARMA AG.
- Model: BR-561156
Aspirin 500 is a tablet medicine containing 500 mg of acetylsalicylic acid – a substance that relieves pain, lowers fever and has an anti-inflammatory effect. According to the approved leaflet, it is intended for adults and adolescents aged 16 years and over.
It is used for the symptomatic treatment of fever and mild to moderate pain, for example headache, flu-like aches, toothache and muscle pain. It relieves symptoms but does not treat their cause.
Important warning
- Supply status in Serbia: available without a prescription (according to the leaflet approved by ALIMS).
- The medicine must not be given to children and adolescents under 16 years (risk of Reye's syndrome).
- Do not take it if you have a stomach or intestinal ulcer, a bleeding tendency, take oral anticoagulants or are in the third trimester of pregnancy.
- Without medical advice, do not take it for more than 3 days for fever or more than 3 to 4 days for pain.
- Use the medicine only in line with the official leaflet and the advice of your doctor or pharmacist.
- This page is for information only and is not an offer to buy the medicine online.
What is Aspirin 500 used for and how should the tablets be taken?
Key facts about the medicine
| Name of the medicine | Aspirin® 500, 500 mg, tablets |
|---|---|
| Active substance | acetylsalicylic acid |
| Strength | 500 mg per tablet |
| Pharmaceutical form | tablet |
| Therapeutic group | analgesic and antipyretic (non-steroidal medicine for pain and fever) |
| Pack | 20 tablets (2 blisters of 10 tablets) |
| Marketing authorisation holder | Bayer d.o.o. Beograd |
| Supply status (Serbia) | available without a prescription |
What is Aspirin 500 used for?
According to the patient leaflet, Aspirin 500 is used in adults and adolescents aged 16 and over for the symptomatic treatment of:
- fever
- mild to moderate pain – for example headache, flu-like aches, toothache and muscle pain
How is it taken and dosed?
Usual dosage according to the leaflet, unless your doctor prescribes otherwise:
| Group | Single dose | Interval between doses | Maximum per day |
|---|---|---|---|
| adults and adolescents aged 16+ | 1–2 tablets | at least 4 hours | 6 tablets |
| people over 65 | 1 tablet | at least 4 hours | 4 tablets |
| children under 16 | must not be used | – | – |
- Method: swallow the tablet with plenty of water.
- Do not take on an empty stomach.
- Duration without medical advice: no more than 3 days for fever or 3–4 days for pain.
Special patient groups
- Children and adolescents under 16: the medicine must not be used (except for the special indication of thrombosis prevention during heart surgery, decided by a doctor).
- Elderly (65+): the single dose is 1 tablet, no more than 4 tablets per day.
- Liver or kidney impairment and circulatory problems (e.g. heart weakness, serious bleeding): caution and prior medical advice are needed; severe impairment is a contraindication.
Contraindications – when the medicine must not be used
- age under 16 years (except the special cardiac surgery indication)
- allergy to acetylsalicylic acid, other salicylates or any of the excipients
- asthma or a severe allergic reaction previously caused by acetylsalicylic acid or other NSAIDs
- stomach or intestinal ulcer
- bleeding or a risk of bleeding
- severe kidney, liver or heart disease
- methotrexate at doses above 15 mg per week
- concomitant oral anticoagulants
- third trimester of pregnancy (after week 24)
Precautions and warnings
- Do not combine with other medicines containing acetylsalicylic acid – risk of overdose.
- Long-lasting headache despite high doses of painkillers needs medical advice, not a higher dose.
- Regular use of painkillers, especially combinations, may reduce kidney function.
- Caution in G6PD deficiency, a history of ulcer, bleeding or gastritis, asthma, kidney or liver impairment and heavy menstrual bleeding.
- If bleeding occurs during treatment (blood in the stool, black stool, bleeding in the mouth), stop treatment immediately and seek help.
- The medicine increases the risk of bleeding for several days after intake – tell your doctor or dentist before surgery or a tooth extraction.
- The medicine reduces uric acid excretion, which is relevant in gout.
Interactions with other medicines, alcohol and food
The medicine must not be taken with methotrexate above 15 mg per week, or with oral anticoagulants if you have had an ulcer. Consult a doctor or pharmacist before use if you take:
- oral anticoagulants, heparins, thrombolytics, clopidogrel or ticlopidine
- other NSAIDs
- glucocorticoids at high doses
- uricosuric medicines for gout (benzbromarone, probenecid)
- diuretics, ACE inhibitors or angiotensin II antagonists
- methotrexate up to 15 mg per week, pemetrexed, anagrelide, deferasirox
- SSRI antidepressants (citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline)
- antacids, gastrointestinal medicines and medicinal charcoal
The leaflet does not list specific interactions with alcohol; the medicine should not be taken on an empty stomach.
Pregnancy and breastfeeding
In the first and second trimester the medicine should only be used on a doctor's advice. From the beginning of the sixth month of pregnancy (after week 24) it must not be taken, as it can seriously harm the mother and the baby.
The medicine passes into breast milk and, as a precaution, is not recommended during breastfeeding. It may temporarily reduce fertility in women.
Driving and using machines
According to the leaflet no special precautions are needed – the medicine does not affect the ability to drive or use machines.
Possible side effects
The frequency of side effects is not known. Tell your doctor immediately if you notice:
- bleeding (nose, gums, red spots under the skin), bleeding in the digestive tract, rarely bleeding in the brain
- stomach pain; narrowing of the bowel (especially with long-term use)
- allergic reactions: rash, itching, difficulty breathing, facial swelling
- headache, dizziness, ringing in the ears and a feeling of reduced hearing (usually a sign of overdose)
- raised liver enzymes or liver damage
- Reye's syndrome in children with a viral illness
Suspected side effects can be reported to your doctor, pharmacist or the Medicines and Medical Devices Agency of Serbia (ALIMS).
Overdose, missed dose and stopping treatment
- Overdose: ringing in the ears, a feeling of hearing loss, headache and dizziness. Stop taking the medicine and contact a doctor immediately.
- Missed dose: do not take a double dose to make up for a missed one.
- Stopping: take the medicine only while symptoms last, within the permitted duration; stop immediately in case of bleeding or an allergic reaction.
When to seek medical help immediately?
- black or bloody stools, vomiting blood or bleeding in the mouth
- facial swelling, difficulty breathing or a severe skin reaction
- ringing in the ears and hearing loss with dizziness (possible overdose)
- in a child who has taken the medicine: dizziness, fainting, unusual behaviour or vomiting
- fever or pain that does not settle after 3 days (fever) or 3–4 days (pain)
Pharmacist's advice
Take the tablets after a meal with a full glass of water and keep at least 4 hours between doses. If you also use other cold or pain remedies, check their ingredients – many contain acetylsalicylic acid.
If you regularly take blood thinners, blood pressure medicines or antidepressants, ask a pharmacist before the first tablet whether Aspirin 500 is a safe choice for you.
Availability and price
The medicine is available without a prescription but cannot be ordered online. This page is for information only.
Please contact a pharmacy to check availability and dispensing conditions.
Composition, packaging and manufacturer
- Each tablet contains 500 mg acetylsalicylic acid.
- Excipients: cellulose (powder) and maize starch.
- Appearance: round white tablets embossed with the Bayer mark on one side and "ASPIRIN 0,5" on the other.
- Pack: 2 blisters (PP/Al) of 10 tablets – 20 tablets in total.
- Marketing authorisation holder: Bayer d.o.o. Beograd, Omladinskih brigada 88b, Belgrade.
- Manufacturer: Bayer Bitterfeld GmbH, Bitterfeld-Wolfen, Germany.
Storage
- Store below 30 °C.
- Do not use after the expiry date stated on the pack.
- Keep out of the sight and reach of children.
- Return unused medicine to a pharmacy that collects unused medicines.
Frequently asked questions
How many Aspirin 500 tablets can I take per day?
Adults and adolescents aged 16 and over take 1–2 tablets at least 4 hours apart, no more than 6 tablets a day. People over 65 take 1 tablet at a time, no more than 4 tablets a day.
Can Aspirin 500 be taken on an empty stomach?
No. According to the leaflet, the medicine should not be taken on an empty stomach, and the tablet should be swallowed with plenty of water.
Can children and teenagers take Aspirin 500?
No. The medicine must not be used in people under 16, especially during viral illnesses such as flu or chickenpox, because of the risk of Reye's syndrome.
Should Aspirin be stopped before a tooth extraction?
Acetylsalicylic acid increases the tendency to bleed for several days after intake. Always tell your dentist or surgeon that you have taken it; they will decide what is needed.
Related information
For additional care and support with headache and pain, see also the Headaches, migraines and vertigo category – products in this category do not replace the medicine you have been prescribed.
Sources
Sources checked on: 23 October 2026.
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