Gino-daktanol 200 mg vaginal suppositories – miconazole for vaginal fungal infections

Gino-daktanol vaginal suppositories (pessaries) contain miconazole (as miconazole nitrate, 200 mg per suppository). Miconazole is a broad-spectrum antifungal of the imidazole group with additional antibacterial action: it kills fungi and some Gram-positive bacilli and cocci.

According to the patient leaflet, Gino-daktanol is used to treat fungal infections of the vagina, whose signs include itching, redness and a whitish discharge. The marketing authorisation holder is Galenika AD Belgrade.

What are Gino-daktanol vaginal suppositories used for and how are they used correctly?

Key facts about the medicine

What is Gino-daktanol used for?

Gino-daktanol vaginal suppositories are used to treat fungal infections of the vagina. Signs of these infections are itching, redness and a whitish discharge. The suppositories kill the fungi causing the infection, as well as some of the bacteria that may also be present.

How is it used and dosed?

• The medicine is for vaginal (local) use only.
• Always wash your hands thoroughly before use.
• Do not stop treatment when itching and other signs of inflammation disappear after a few days – symptoms may return.
• During treatment, do not insert other vaginal suppositories or a diaphragm into the vagina and avoid tampons.
• If you feel the effect is too strong or too weak, talk to your doctor.

Special patient groups

• Children: Gino-daktanol is not used in children.
• Partner: if the partner is also infected, he may need treatment too, to avoid re-infection.
• Women on anticoagulant therapy: the doctor may check the effect of warfarin during treatment.

Contraindications – when the medicine must not be used

Do not use Gino-daktanol:

• if you are allergic to miconazole nitrate, other similar antifungals (imidazole derivatives) or the excipient (hard fat H-15);
• if you have previously had an allergic reaction to Gino-daktanol vaginal suppositories.

Warnings and precautions

Before and during use, note the following:

• severe hypersensitivity reactions, including anaphylaxis and angioedema, have been reported with miconazole products – if hypersensitivity or irritation occurs, treatment should be stopped;
• do not use latex condoms or diaphragms at the same time;
• take measures to prevent spreading the infection – do not let others use your underwear or towels;
• the medicine does not stain skin or clothing.

Interactions with other medicines, food and drink

Because absorption after vaginal use is low, clinically significant interactions are very rare. Nevertheless, tell your doctor or pharmacist if you use:

• oral anticoagulants, e.g. warfarin – their effect needs monitoring;
• medicines for diabetes (oral hypoglycaemics) or phenytoin;
• simvastatin or lovastatin;
• calcium channel blockers (e.g. dihydropyridines, verapamil).

With these medicines, miconazole may increase their effect and the frequency of side effects. Avoid contact of the suppositories with latex products.

Pregnancy and breast-feeding

• Pregnancy: miconazole is absorbed into the bloodstream only to a very small extent. Animal studies showed no harmful effects, but the doctor weighs benefits and risks and decides whether you can use the medicine.
• Breast-feeding: it is not known whether miconazole passes into breast milk – caution is needed.

Driving and using machines

Gino-daktanol has no influence on the ability to drive or use machines.

Possible side effects

Like all medicines, Gino-daktanol can cause side effects, although not everybody gets them.

• Very common (more than 1 in 10): genital itching, vaginal discomfort and burning.
• Common (up to 1 in 10): skin rash, menstrual pain.
• Uncommon (up to 1 in 100): itchy rash, hives.
• Not known: hypersensitivity including anaphylactic reactions, itching, angioedema, vaginal irritation, pelvic cramps, application-site irritation.

Vaginal discharge and bleeding, vaginal pain, headache, painful urination, urinary tract infection, abdominal pain, rosacea, facial swelling and nausea were also reported in clinical studies, but a causal relationship with the medicine was not established.

Overdose, missed dose and stopping treatment

• Overdose / accidental swallowing: if someone accidentally swallows a suppository, seek medical advice immediately.
• Missed dose: do not use a double dose; use the next dose at the usual time and continue as scheduled.
• Stopping treatment: continue for as long as the doctor prescribed – if you stop early, symptoms may come back.

Related information

For care and support of the intimate flora, see also the category Products for vaginal yeast discomfort – products in this category do not replace the medicine prescribed to you.

Composition, pack and manufacturer

• Active substance: each vaginal suppository contains 200 mg miconazole nitrate.
• Excipient: hard fat H-15.
• Pack: ALU/PE-ALU/PE strip or PVC/PE strip with 7 vaginal suppositories, in a carton with leaflet.
• Marketing authorisation holder: Galenika AD Belgrade, Batajnički drum b.b., Belgrade.
• Manufacturers: Galenika AD Belgrade; Bionika Pharmaceuticals d.o.o., Str Skupi No 57, Skopje, North Macedonia.
• Marketing authorisation: 000456308 2023 of 24 April 2024.

Storage

• Store below 25 °C in the original package.
• Keep out of the sight and reach of children.
• Do not use after the expiry date; return unused medicine to a pharmacy that collects unused medicines.

Frequently asked questions

How long are Gino-daktanol suppositories used?

One suppository every evening before bedtime for 7 consecutive days. Treatment is not interrupted during menstruation or when symptoms disappear earlier.

Can I use a condom during Gino-daktanol treatment?

Not latex condoms or diaphragms – Gino-daktanol may damage latex and reduce its effectiveness. Ask your doctor or pharmacist about other methods of protection.

Does my partner need treatment?

If the partner is also infected, appropriate treatment is needed for him as well to prevent re-infection. The doctor decides on this.

Can Gino-daktanol be used during menstruation?

Yes. According to the leaflet, treatment continues during menstruation, and tampons should be avoided.

Sources

• ALIMS – Summary of Product Characteristics, Gino-daktanol® 200 mg vaginal suppositories (SmPC, Serbian)
• ALIMS – Patient leaflet, Gino-daktanol® 200 mg vaginal suppositories (PIL, Serbian)

Sources checked on: 25 October 2026.