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1,999.00 RSD
7 samples sold

Product Description



a safe alternative to botox injections

Innovative & Natural anti-age ingredients for a face without wrinkles

BOTOFILL cream contains an innovative cosmetically active ingredient with a Botox effect

 ARGIRELIN hexapeptide in the maximum recommended concentration of 10%.

ARGIRELIN hexapeptide has a mechanism of action like Botulinum Toxin.

 It acts directly on muscle contraction, leads to relaxation of the muscles responsible for the formation of mimic wrinkles and reduces the depth of wrinkles.

 Visible effects were observed after 7 days of application.

 Studies have shown that it prolongs the effect of Botox injections.

When moving the face, the facial muscles contract (spasm). Frequent repetition of the same movements leads to wrinkling of the skin and the formation of wrinkles. These are so-called mimic wrinkles caused by facial expressions. Muscle contractions occur when nerve cells secrete neurotransmitters into the synaptic space (the space between the nerve and the muscle cell), which then act directly on the muscle cells, causing the muscles to contract. The protein SNARE complex located in the nerve cell is responsible for the release of neurotransmitters into the synaptic space and causing muscle contraction. -Botulinum toxin works by breaking down SNAP-25 proteins from the SNARE complex, thus preventing the secretion of neurotransmitters and blocking muscle contraction, which causes muscle paralysis and tightening of the facial skin.

Argireline hexapeptide binds to the SNARE complex, displaces SNAP-25 protein and takes its place in the SNARE complex, which leads to a weakening of muscle contraction and a reduction in the depth of wrinkles caused by muscle contraction.

Active ingredients of Botofill cream:

 Argireline, 10% with a Botox effect that acts on mimic wrinkles

 Sodium hyaluronate to fill fine wrinkles on the whole face

 Panthenol for skin hydration

 Vitamin E as an antioxidant

 Marigold extract with a calming effect

 Avocado oil that nourishes the skin and stimulates collagen synthesis

 Bisabolol for better penetration of active ingredients into deeper layers of the skin

Botofill cream is recommended for regular facial care in order to achieve an anti-aging effect, as well as for facial care in the period between two Botox injections.

Method of application: The cream is applied by light rubbing in the evening before going to bed on previously cleansed skin.

Packaging: 50 g

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Pharmacy Online has a contract with the Daily Express courier service and it is delivered on the territory of the Republic of Serbia through this service. Exports of goods to foreign countries are done through DHL and PostExport.

For all orders received up to 12h from Monday to Friday, the approximate delivery time is 2-4 business days for the whole territory of the Republic of Serbia. In case the order is placed on weekends (Saturdays and Sundays), the delivery is done as well as for the orders received on Monday - so next business day.

Deliveries are not made on Saturdays and Sundays.

Additional information

The items will be packed so that they cannot be damaged by normal handling of the goods in transit. When picking up the product, the buyer is obliged to check for any damage and immediately advertise it to the courier who delivered the goods, or refuse to take over the shipment, which shows the external damage. Any subsequent product claims for shipping damage will not be considered.

When picking up the product, the customer is required to sign the delivery note taken by the Daily Express delivery worker. The delivery note is considered to be a receipt and delivery note.

The courier service delivers the goods to the address, ie. does not bring into the living space.

Delivery restrictions on goods

Delivery of items purchased on the site www.apotekaonline.rs is made exclusively through the Daily Express courier service in the territory of the Republic of Serbia. Delivery outside the territory of the Republic of Serbia, ie export of goods, is done exclusively through the service of DHL and PostExport Post of Serbia.

Shipping cost

For the territory of the Republic of Serbia:

For goods ordered up to 5.000,00 RSD, delivery charge is 260.00 RSD (VAT included). For goods over 5.000,00 RSD, shipping is free of charge.

For international delivery:

For the export of goods abroad through the PostExport service of Post of Serbia, the shipping price is for:

  • Zone I (Slovenia, Croatia, Bosnia and Herzegovina, Montenegro, Northern Macedonia) - 1,280.00 RSD
  • Zone II (Other European countries) - 1,790.00 RSD
  • Zone III (Asia, Africa, America, Australia and other countries) - 2,650.00 RSD

Delivery time is 15 days or more (depending on the country of delivery)

For export of goods abroad through DHL service, the shipping price is 2,700.00 RSD. Delivery time is 1-5 business days (depending on the country of delivery)

Shipping cost is with tax. The price includes the delivery of the parcel to the buyer's address with the associated tax and customs at the seller's expense. A possible additional cost may be a customs charge against the buyer, depending on the country to which the package is being shipped.

For any additional questions, complaints or checking the current location of your shipment, please contact us at the following e-mail address: [email protected]

Tags: botofill , krema